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Fat component of inflammatory bowel disease formula food for special medical purpose and preparation method thereof

A technology of inflammatory bowel disease and formula food, applied in the direction of edible oil/fat, application, food science, etc., can solve the problem of relatively rough category limitation, and achieve the effects of shortening hospitalization time, easy digestion and absorption, and reasonable matching

Active Publication Date: 2021-04-23
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Dietary fat intake and fat composition are important factors affecting the onset of IBD. At present, the special nutritional formula for patients with inflammatory bowel disease in the domestic market is in the initial stage of research and development. The special medical formula for patients with inflammatory bowel disease Foods have relatively rough restrictions on the amount of fat intake and the type of fat intake. How to prepare a fat formula food for special medical purposes that relieves and prevents the recurrence of inflammatory bowel disease is a technical problem to be solved in this field

Method used

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  • Fat component of inflammatory bowel disease formula food for special medical purpose and preparation method thereof
  • Fat component of inflammatory bowel disease formula food for special medical purpose and preparation method thereof
  • Fat component of inflammatory bowel disease formula food for special medical purpose and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 3

[0064] Embodiment 3 (comparative example):

[0065] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0066] Medium-chain triglycerides: 70%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0067] Nutritional oils: 5.5% linseed oil, 4.5% seabuckthorn seed oil, 7.5% olive oil, 2.5% tea seed oil, 5.5% rice bran oil, 4.5% peanut oil.

[0068] Preparation method is with specific embodiment 1.

[0069] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0070] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0071] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat co...

Embodiment 4

[0073] Embodiment 4 (comparative example):

[0074] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0075] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0076] Nutritional oils: cottonseed oil 25%, soybean oil 18%, sunflower oil 17%.

[0077] Preparation method is with specific embodiment 1.

[0078] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0079] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0080] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0081] The HE stainin...

Embodiment 5

[0082] Embodiment 5 (comparative example):

[0083] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0084] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0085] Nutritional oils: tea seed oil 17%, rice bran oil 21%, peanut oil 22%.

[0086] Preparation method is with specific embodiment 1.

[0087] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0088] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0089] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0090] The HE staining l...

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Abstract

The invention discloses a fat formula food which can be used for special medical purposes of patients with inflammatory bowel disease and a preparation method thereof. The fat component of the present invention includes the following raw materials in weight percentage: 40% medium-chain triglycerides (tricaprylic acid glyceride: tricapric glyceride mass ratio is 3:1) and includes linseed oil 11%, seabuckthorn seed oil 14%, Nutritious oils composed of 13% olive oil, 7% tea seed oil, 11% rice bran oil, and 4% peanut oil. The product of the invention has balanced nutritional components, reasonable fatty acid composition, contains MCT lipids required by patients with inflammatory bowel disease, and is rich in anti-inflammatory active ingredients such as polyphenols, phytosterols and oryzanol, which are easily digested and absorbed by the human body, and are effective for patients with inflammatory bowel disease. Has significant palliative and preventive effects.

Description

technical field [0001] The invention belongs to the technical field of formula food for special medical use, and in particular relates to a fat component of formula food for special medical purpose of inflammatory bowel disease and a preparation method thereof. Background technique [0002] Inflammatory bowel disease (IBD) is a chronic inflammation of the intestinal tract caused by various etiologies and mediated by abnormal immunity. ,) and ulcerative colitis (Ulcerative Colitis, UC). [0003] Malnutrition is the most common systemic manifestation in IBD patients and may occur at any stage of inflammatory bowel disease. At present, drugs such as aminosalicylic acid, glucocorticoids, and immunosuppressants are the main treatment measures for this disease, but in some cases, the efficacy of drugs is not good, and adverse drug reactions are prone to occur. Studies have shown that in the early and mid-term treatment of patients with inflammatory bowel disease, targeted nutrit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23D9/00A23D9/04
Inventor 刘睿杰郭怡雯常明张涛裘芳成金青哲王兴国
Owner JIANGNAN UNIV
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