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Biochemical calibrator calibration method and preparation method of biochemical reagent combined calibration product

A calibration method and calibrator technology, applied in the direction of instruments, scientific instruments, measuring devices, etc., can solve problems such as changes, achieve the effect of improving accuracy, improving quality and speed, and improving overall quality requirements

Inactive Publication Date: 2019-05-24
河北艾欧路生物科技有限责任公司
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Problems solved by technology

Direct bilirubin is decomposed by light, which can easily lead to changes in the final value during production and storage

Method used

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  • Biochemical calibrator calibration method and preparation method of biochemical reagent combined calibration product

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Embodiment Construction

[0057] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0058] like figure 1 As shown, the present invention provides a technical solution: a calibration method of a biochemical calibrator, including a biochemical calibrator, comprising the following steps:

[0059] 1) Selected calibrators and quality controls

[0060] ①The calibrator contains a known amount of the substance to be measured, which is used to calibrate the value of the determination method. It is associated with the method, reagents, and instruments. The function of...

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Abstract

The invention relates to the technical field of biochemical reagent combined calibration. The quality and speed of clinical examination are increased, the labor intensity of inspectors is lowered, samples and reagents are reduced, the detection precision is improved, errors are reduced, and the standardization of the clinical examination is realized. A series of experiments prove that biofilms with different molecular weights have different permeation degrees for different substances and within different times. The content of each substance in serum is increased by biofilm serum concentration,the substances with different molecular weights can permeate the biofilms with the different molecular weights, and target substances are calibrated in a high-concentration combined way; the different substances are mixed together, the concentration required in each item of the combined calibration is achieved, the dissolution and valuing problems of special substances such as total bilirubin, bile acid, triglyceride and uric acid are well solved, the problems of unstable calibration and clinical trench effect are also solved, and the clinical measured values are enabled to be close to true values.

Description

technical field [0001] The invention relates to the technical field of biochemical reagent composite calibration, in particular to the calibration of a biochemical calibrator and a preparation method for biochemical reagent composite calibration thereof. Background technique [0002] Biochemical reagents have been widely used in clinical practice, and their traceable calibration technology has a high threshold. Due to the many items, complex added substances, and more difficult value determination, we usually use imported calibration products from Landau, Roche or Bio-Rad. The domestically produced ones cannot be produced, and some of the items produced are incomplete, and the fixed values ​​of the items are not allowed, which makes it impossible to realize clinical use. For example: simple total bilirubin does not dissolve in water matrix, but dissolves in chloroform, but the addition of chloroform will destroy the protein in serum. Direct bilirubin is decomposed by light,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/00G01N21/31G01N33/573
Inventor 庞刚邹志良王素玉王煌煌
Owner 河北艾欧路生物科技有限责任公司
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