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Medical composition capable of reducing weight and reducing blood lipid and preparation method and use of medical composition

A composition and pharmaceutical preparation technology, applied in the field of weight loss and lipid-lowering pharmaceutical composition and its preparation, can solve the problems of high recurrence rate, long-term medication, easy rebound, etc.

Active Publication Date: 2019-05-03
CATCH BIO SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical first-line drugs for lowering blood lipids are mainly statins, which have definite curative effect and quick onset, but have the disadvantages of easy rebound, high recurrence rate, and the need for long-term medication.
In 2001, cerivastatin was withdrawn from the market due to serious adverse reactions caused by rhabdomyolysis and death, which also aroused concerns and heated discussions about the safety of other statins
[0005] Although there are literature reports in the prior art that phlorizin has hypolipidemic effect, and there are also literature reports that dihydromyricetin can significantly reduce the weight of mice with hyperlipidemia, but there is no pharmaceutical composition composed of phlorizin and dihydromyricetin Relevant reports on blood fat-lowering or weight-loss effects

Method used

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  • Medical composition capable of reducing weight and reducing blood lipid and preparation method and use of medical composition
  • Medical composition capable of reducing weight and reducing blood lipid and preparation method and use of medical composition

Examples

Experimental program
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Effect test

Embodiment 1

[0056] The raw materials of the pharmaceutical composition in this embodiment consist of: 42 g of phlorizin and 58 g of dihydromyricetin.

[0057] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of phlorizin and dihydromyricetin, grind them, and mix them uniformly to obtain the product.

[0058] The pharmaceutical composition of this embodiment is prepared into tablets by adding conventional excipients and following conventional techniques.

Embodiment 2

[0060] The raw materials of the pharmaceutical composition in this embodiment consist of: 25 g of phlorizin and 75 g of dihydromyricetin.

[0061] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of phlorizin and dihydromyricetin, grind them, and mix them uniformly to obtain the product.

[0062] The pharmaceutical composition of this embodiment is prepared into capsules by adding conventional excipients and following conventional techniques.

Embodiment 3

[0064] The raw materials of the pharmaceutical composition in this embodiment consist of: 65 g of phlorizin and 35 g of dihydromyricetin.

[0065] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of phlorizin and dihydromyricetin, grind them, and mix them uniformly to obtain the product.

[0066] The pharmaceutical composition of this example is prepared into granules by adding conventional excipients and following conventional techniques.

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Abstract

The invention relates to a medical composition capable of reducing weight and reducing blood lipid and a preparation method and use of the medical composition. The medical composition comprises the following raw medicines: 15-65 parts by weight of phloridzin or pharmaceutically acceptable salt thereof based on weight of phloridzin, and 20-75 parts by weight of dihydromyricetin or pharmaceuticallyacceptable salt thereof based on weight of the dihydromyricetin. The medical composition has significant effect of reducing weight, and has synergetic effects, and the effect of the medical composition for reducing weight is much better than that of a single raw medicine for reducing weight; the medical composition has significant effect of reducing blood lipid, and has synergetic effects, and theeffect of the medical composition for reducing blood lipid is much better than the effect of the single raw medicine for reducing blood lipid.

Description

technical field [0001] The invention belongs to the field of health care products or medicines, and relates to a medicinal composition for weight loss and fat reduction, a preparation method and application thereof. Background technique [0002] Obesity is one of the most common chronic endocrine and metabolic diseases, and its incidence is increasing year by year, which has become a global public health problem. Body mass index (BMI) is generally used to indicate the degree of obesity. According to the international standard formulated by the World Health Organization (WHO) expert meeting, 24≤BMI<28 is overweight, and BMI>30 is obesity. According to the statistics of WHO, more than 1 billion adults in the world are currently overweight, and at least 300 million of them are obese. If no effective measures are taken, the number of overweight people will reach 1.5 billion by 2015. Obesity can cause many health problems, not only increasing the morbidity and mortality o...

Claims

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Application Information

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IPC IPC(8): A61K31/7034A61K31/352A61K36/9066A61K36/605A61P3/06A61P3/04
Inventor 温尧林
Owner CATCH BIO SCI & TECH
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