Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for transdermal delivery, comprising nanoemulsion and modified layered double hydroxide

A technology of composition and nanoemulsion, which is applied in the field of personal beauty or care composition, preparation of composition for transdermal delivery, and can solve the problem of reducing the biological activity of functional raw materials

Active Publication Date: 2019-04-16
H&A PHARMACHEM
View PDF8 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, light, heat, and oxygen in the air are known to severely reduce the biological activity of functional raw materials

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for transdermal delivery, comprising nanoemulsion and modified layered double hydroxide
  • Composition for transdermal delivery, comprising nanoemulsion and modified layered double hydroxide
  • Composition for transdermal delivery, comprising nanoemulsion and modified layered double hydroxide

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0047] Preparation Example 1: Preparation of Layered Double Hydroxide (LDH)

[0048] 1-1: Synthesis of ZnAl-carbonate LDH (c-LDH)

[0049] ZnAl-LDH containing carbonate ions was synthesized by the following coprecipitation method. In 0.2M Zn(NO 3 ) 2 and 0.1M Al(NO 3 ) 3 Slowly add 1M Na to the mixed solution 2 CO 3 solution until the final pH becomes around 7.0. The mixed solution was stored in an oven at about 70° C. for about one day, filtered, washed with distilled water and ethanol, and dried with a vacuum pump. The possible structural formula of the synthesized c-LDH is as follows: [Zn 4 al 2 (OH) 12 ]CO 3 ·xH 2 O.

[0050] 1-2: ZnAl-carbonate LDH surface-treated with stearic acid (SA) Synthesis of (SA-LDH)

[0051] 100 g of ZnAl-carbonate LDH and 3 g of stearic acid were dissolved in 100 ml of distilled water, and the mixed solution was stirred at 80° C. for 2 hours. The resulting substance was filtered, washed with distilled water and ethanol, an...

preparation example 2

[0057] Preparation Example 2: Preparation of Nanoemulsion Containing Moisturizer

[0058] According to the composition of the following Table 1, the ingredients were introduced into the container, and dissolved at a temperature of 50°C, and then mixed with a homomixer for 5 minutes, and then passed continuously at 800 bar (bar) in a high-pressure homogenizer 5 times, then cooling and defoaming are performed to obtain nanoemulsions containing humectants.

[0059] [Table 1]

[0060]

[0061]

preparation example 3

[0062] Preparation Example 3: Preparation of Nanoemulsion Containing Whitening Agent

[0063] A nanoemulsion was prepared by the same method as Preparation Example 2 except that the ingredients were used in the composition of Table 2 below.

[0064] [Table 2]

[0065]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
sizeaaaaaaaaaa
sizeaaaaaaaaaa
Login to View More

Abstract

The present invention relates to: a composition for transdermal delivery, comprising 1) a nanoemulsion comprising an active ingredient, saturated lecithin, phytosteryl / behenyl / octyldodecyl lauroyl glutamate, a polyol, and water, and 2) a modified layered double hydroxide; and a preparation method therefor.

Description

technical field [0001] The present invention relates to a composition for transdermal delivery, in more detail, to a composition for transdermal delivery comprising 1) a nanoemulsion comprising active ingredients, saturated lecithin, phytosterol / behenyl Alcohol / octyldecyl lauroyl glutamate, polyol and water; and 2) modified layered double hydroxide. [0002] Furthermore, the present invention relates to a composition for personal beauty or personal care comprising said composition for transdermal delivery. [0003] Furthermore, the present invention relates to a process for the preparation of a composition for transdermal delivery comprising the steps of: i) combining the active ingredient, saturated lecithin, phytosterol / behenyl alcohol / octyldecyl lauroyl glutamic acid preparing nanoemulsion after mixing ester, polyol and water; ii) mixing the nanoemulsion prepared in the step (i) with modified layered double hydroxide to form a complex. Background technique [0004] In o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/06A61K8/55A61K8/34A61K8/73A61K8/68A61K8/67A61K8/9789A61K8/64A61K8/92A61Q19/00
CPCA61K8/34A61K8/55A61K8/64A61K8/67A61K8/68A61K8/73A61Q19/00A61K8/92A61K8/97A61K8/06A61K31/194A61K31/573A61K9/1075A61K9/0014A61K47/14A61K47/10A61K47/24A61K47/02A61P17/00A61P17/02A61P17/14A61P29/00A61P3/02A61P31/04A61P5/24A61K8/9794A61K8/9789A61K8/553A61K8/735A61K8/922A61K2800/413A61K8/27A61K8/345A61K8/368A61K8/463A61K8/60A61K8/63A61K9/107A61K47/28A61Q7/00A61Q17/04A61Q19/007A61Q19/02
Inventor 李种贤曺世熙禹玲珑朴宁娥池洪根
Owner H&A PHARMACHEM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com