A method for staining the anterior lens capsule in overmature cataract surgery

A cataract and lens technology, applied in the medical field, can solve problems such as difficulty in buying ophthalmology channels, visual cytotoxicity, dye toxicity, etc.

Active Publication Date: 2021-01-26
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (1) The dyes in the existing technology need to be prepared separately, because they have not formed an industrial scale and are used for external indications, so it is difficult to buy them from regular ophthalmology channels
[0007] (2) the dyeing agent in the prior art has certain toxicity
[0010] The dyes in the prior art have certain toxicity, and have certain toxicity to corneal endothelial cells, visual cells, etc.

Method used

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  • A method for staining the anterior lens capsule in overmature cataract surgery
  • A method for staining the anterior lens capsule in overmature cataract surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Patient Gao Yufang, female, 99 years old, had cataracts for many years;

[0047] Due to advanced age and many systemic complications, surgery has not been performed. On August 29, 2017, cataract surgery was performed at the Affiliated Hospital of Qingdao University.

Embodiment approach 1

[0049] Preoperatively dilate mydriasis three times with compound tropicamide eye drops, intramuscularly inject 50mg / kg mixture of ketamine hydrochloride and chlorpromazine hydrochloride after anesthesia, make an upper limbal incision, inject 0.2% methylene into the anterior chamber Blue injection 0.1ml, after staying in the anterior chamber for 10s, fully rinse with compound sodium chloride injection for 30s;

[0050] Inject an appropriate amount of viscoelastic, perform continuous circular capsulorhexis, and observe the tissue contrast;

[0051] If the toughness of the degenerated capsule increases, and the capsulorhexis needle or tweezers are difficult to complete the operation, it is necessary to use the capsule scissors to trim and continue the capsulorhexis. Although the capsulorhexis opening cannot be perfectly round, it can also ensure a smooth capsulorhexis opening;

[0052] Use the Millennium phacoemulsification system for phacoemulsification, the perfusion / suction sy...

Embodiment approach 2

[0054] The patient lies supine on the operating table, routine eyewashing, disinfection, draping, under retrobulbar anesthesia or topical anesthesia, standard corneal tunnel incision and limbal auxiliary incision are used, sterile air is injected into the anterior chamber, and the nurse draws 2ml of venous blood from the patient. The upper assistant uses a 1ml syringe to draw 1ml of venous blood from the 2ml syringe used to draw blood, replaces the flushing needle, injects about 0.1ml of venous blood into the center of the anterior capsule, and rinses the anterior chamber with BSS solution after 10 seconds to clear the anterior chamber. For excess blood, viscoelastic agent is injected into the anterior chamber, and continuous circular capsulorhexis is performed with a capsulotomy needle or capsulorhexis forceps. At this time, the anterior lens capsule is stained with blood, and the tearing boundary is clearly visible, and the pulling is adjusted at any time according to the pred...

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Abstract

The invention belongs to the field of medical technology, and discloses a method for staining the anterior lens capsule in overmature cataract surgery. Take 240 clean-grade male Wistar rats with a body weight of 200-250 g; the animals are randomly divided into a normal control group and an experimental group; The experimental group was dilated with compound tropicamide eye drops three times before operation, anesthetized by intramuscular injection of a mixture of ketamine hydrochloride and chlorpromazine hydrochloride, then made an upper limbal incision, injected methylene blue injection into the anterior chamber, and stayed in the anterior chamber Afterwards, fully flush with compound sodium chloride injection; inject appropriate amount of viscoelastic agent, continuously circular capsulorhexis, observe tissue contrast; continue capsulorhexis after trimming with capsular shears. The present invention does not require additional preparation, can be taken at any time, and has good biocompatibility; it has no drug chemical toxicity to intraocular tissues, such as corneal endothelial cells and visual cells; residual traces can be discharged through normal intraocular absorption or aqueous humor circulation; no Obvious complications.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a method for staining the anterior lens capsule in overmature cataract surgery. Background technique [0002] At present, the existing technologies commonly used in the industry are as follows: [0003] Advanced cataract is an eye disease that seriously affects vision. Modern ophthalmic surgery can completely restore vision and even improve visual function in cataract patients. Cataract phacoemulsification combined with intraocular lens implantation has become the mainstream surgical method for cataract treatment. The continuous circular capsulorhexis (CCC) of the anterior lens capsule is an important step, which can be said to be the key to the success of the operation. effect. If the CCC is successfully completed, the operation can basically be successful; if the CCC cannot be completed, the subsequent operations will be difficult, and the probability of complications such a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F9/007A61D1/00A61D7/00
CPCA61D1/00A61D7/00A61F9/00736A61F9/00754
Inventor 姜涛孙哲宗瑶杨雪娇潘晓晶王云霄赵善瑶
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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