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Hyaluronic acid gel and preparation method thereof

A technology of hyaluronic acid and gel, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve problems such as unsatisfactory effects, ineffective freckle removal, dry skin, etc., and achieve the effect of inhibiting skin melanin Forming, good spot lightening and antibacterial effect

Inactive Publication Date: 2019-03-08
济南豪瑞生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the current skin care products on the market also contain hyaluronic acid gel, its effect is not ideal, the effect of removing freckles is not obvious, or there is obvious redness and swelling, or the phenomenon of dry skin appears on the skin. Therefore, it is urgent to find a New hyaluronic acid gel

Method used

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  • Hyaluronic acid gel and preparation method thereof
  • Hyaluronic acid gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The raw material of the hyaluronic acid gel of the present embodiment comprises the following components by weight:

[0063] Hyaluronic acid 70 parts;

[0064] 2 parts of glycerin;

[0065] 1 part of recombinant human epidermal growth factor gel;

[0066] Arbutin gel 3 parts;

[0067] Juniper fruit extract 2 parts;

[0068]Moisturizer 4 parts;

[0069] 2 parts emulsifier;

[0070] 3 parts antibacterial agent;

[0071] Antioxidant 3 parts;

[0072] 2 parts chamomile;

[0073] Purified water 10 parts.

[0074] Wherein, hyaluronic acid includes hyaluronic acid with a molecular weight of 1000 daltons, hyaluronic acid with a molecular weight of 100,000 daltons and hyaluronic acid with a molecular weight of 1 million daltons.

[0075] The humectant is a blend of AHAs, Glycolic Acids and Betaine.

[0076] The emulsifier is isooctyl stearate.

[0077] The antioxidant is niacinamide.

[0078] The antibacterial agent is bisabolol.

[0079] A preparation method of hya...

Embodiment 2

[0086] The raw material of the hyaluronic acid gel of the present embodiment comprises the following components by weight:

[0087] Hyaluronic acid 80 parts;

[0088] 4 parts of glycerin;

[0089] 3 parts of recombinant human epidermal growth factor gel;

[0090] Arbutin gel 5 parts;

[0091] Juniper fruit extract 6 parts;

[0092] 7 parts of moisturizing agent;

[0093] 7 parts of emulsifier;

[0094] 6 parts of antibacterial agent;

[0095] Antioxidant 9 parts;

[0096] Chamomile 8 parts;

[0097] 20 parts of purified water.

[0098] Wherein, hyaluronic acid includes hyaluronic acid with a molecular weight of 2600 daltons, hyaluronic acid with a molecular weight of 300,000 daltons and hyaluronic acid with a molecular weight of 2 million daltons.

[0099] The moisturizer is shea butter.

[0100] The emulsifier is calamine.

[0101] Antioxidant is the grass green salicornia extract.

[0102] Antibacterial agent is Sophora flavescens extract.

[0103] A preparation...

Embodiment 3

[0110] The raw material of the hyaluronic acid gel of the present embodiment comprises the following components by weight:

[0111] Hyaluronic acid 73 parts;

[0112] 3 parts of glycerin;

[0113] 2 parts of recombinant human epidermal growth factor gel;

[0114] Arbutin gel 4 parts;

[0115] Juniper fruit extract 3 parts;

[0116] Moisturizer 4 parts;

[0117] 4 parts emulsifier;

[0118] 4 parts of antibacterial agent;

[0119] Antioxidant 5 parts;

[0120] Chamomile 5 parts;

[0121] 15 parts of purified water.

[0122] Wherein, hyaluronic acid includes hyaluronic acid with a molecular weight of 1600 daltons, hyaluronic acid with a molecular weight of 150,000 daltons and hyaluronic acid with a molecular weight of 1 million daltons.

[0123] The humectant is fruit acid.

[0124] The emulsifier is octyldimethylsiloxane.

[0125] The antioxidant is a bifid yeast fermentation product lysate.

[0126] Antibacterial agent is glabra extract.

[0127] A preparation met...

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Abstract

The invention provides hyaluronic acid gel and a preparation method thereof. The hyaluronic acid gel is prepared from hyaluronic acid, glycerin, recombinant human epidermal growth factor gel, arbutingel, a Juniperus communis fruit extract, a moistening agent, an emulsifier, a bacteriostatic agent, an antioxidant, chamomile and purified water. The preparation method comprises the following steps of: mixing the glycerin, the recombinant human epidermal growth factor gel, the arbutin gel and the moistening agent to obtain a first mixture; heating the first mixture, the purified water, the chamomile, the Juniperus communis fruit extract, the bacteriostatic agent, the emulsifier and the antioxidant, and preserving heat to obtain a second mixture; adding the hyaluronic acid into the second mixture, stirring and cooling to obtain the hyaluronic acid gel. By adopting the preparation method, the moistening agent, the emulsifier, the bacteriostatic agent and the antioxidant are combined, so that the formation of skin melanin can be inhibited. The hyaluronic acid gel has better moistening and whitening effects, and further has good effects of fading spots and resisting bacteria, so that theskin can become plump, white, smooth and fine.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a hyaluronic acid gel and a preparation method thereof. Background technique [0002] Hyaluronic acid gel is a natural transparent polysaccharide, which originally existed in the dermal tissue of human skin in the form of gel, responsible for storing water, making the skin look plump, plump and elastic, especially in the process of tissue repair It plays an important role in the wound healing process of the skin; but the hyaluronic acid gel will disappear with age, making the skin lose its ability to store water, gradually becoming dull, aging, and forming fine wrinkles, even worse There are also spots. Although the current skin care products on the market also contain hyaluronic acid gel, its effect is not ideal, the effect of removing freckles is not obvious, or there is obvious redness and swelling, or the phenomenon of dry skin appears on the skin. Therefore, i...

Claims

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Application Information

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IPC IPC(8): A61K8/04A61K8/34A61K8/365A61K8/37A61K8/44A61K8/58A61K8/60A61K8/64A61K8/67A61K8/73A61K8/92A61K8/9728A61K8/9761A61K8/9789A61Q19/00A61Q19/02A61Q17/00
CPCA61K8/042A61K8/34A61K8/345A61K8/365A61K8/37A61K8/44A61K8/585A61K8/602A61K8/64A61K8/675A61K8/735A61K8/922A61Q17/005A61Q19/00A61Q19/02A61K8/9728A61K8/9761A61K8/9789
Inventor 房勇
Owner 济南豪瑞生物技术有限公司
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