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Compounds for promoting human hair growth and/or inhibiting or delaying hair loss and compositions for such use

A technology for hair growth and hair loss, applied in the directions of drug combinations, active ingredients of hydroxy compounds, hair care, etc.

Active Publication Date: 2021-12-14
GIULIANI SPA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] According to Busse et al., there is evidence that natural sandalwood oil and other synthetic sandalwood odorants are not agonists of the olfactory receptor OR2AT4 and do not exhibit the same epidermal wound-healing effects

Method used

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  • Compounds for promoting human hair growth and/or inhibiting or delaying hair loss and compositions for such use
  • Compounds for promoting human hair growth and/or inhibiting or delaying hair loss and compositions for such use
  • Compounds for promoting human hair growth and/or inhibiting or delaying hair loss and compositions for such use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] lotion

[0043] components (INCI name)................................... quantity (w / w%)

[0044] Denatured Alcohol .............................................. 15-35

[0045] PEG-40 Hydrogenated Castor Oil................................0.5-3

[0046] Sandalyl alcohol................................................0.1-10.0

[0047] Ethoxyethylene glycol................................0.25-1.0

[0048] Add appropriate amount of water to 100g

Embodiment 2

[0050] Pre-shampoo Hair Mask (PRE-SHAMPOO MASK)

[0051] components (INCI name)................................... quantity (w / w%)

[0052] Glycerin................................................1.5-4.5

[0053] Ammonium Acryloyldimethyltaurate / vp Copolymer...................1.0-2.0

[0054] Sandalyl alcohol................................................0.1-10.0

[0055] Cyclopentasiloxane................................1.0-2.0

[0056] Phenoxyethanol .............................................0.25-0.75

[0057] Fragrance................................................0.5-1.0

[0058] Caprylyl glycol................................................0.25-0.75

[0059] Phenyl trimethicone...................................0.25-0.75

[0060] Polysiloxane Quaternary Ammonium-17................................0.1-0.4

[0061] Simethicone................................................0.1-0.4

[0062] Laureth-4................................................0.1-0.4

...

Embodiment 3

[0074] Intensive Styling Gel

[0075] components (INCI name)................................... quantity (w / w%)

[0076] Sandalyl alcohol................................................0.1-10.0

[0077] PEG-40 Hydrogenated Castor Oil................................1-3

[0078] Fragrance...................................................0.5-1.5

[0079] Polyacrylate-14................................0.5-1.5

[0080] Hydroxypropyl guar gum................................0.5-1.5

[0081] Hydrogenated starch hydrolyzate................................0.5-1.5

[0082] Sodium hydroxymethylglycinate................................0.25-1.0

[0083] Benzophenone-4................................................0.15-0.45

[0084] Disodium edetate................................0.05-0.15

[0085] Polyquaternium-11................................................0.0025-0.025

[0086] Add appropriate amount of water to 100g

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PUM

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Abstract

The present invention relates to the use of compounds of general formula (I) for promoting hair growth in human scalp and / or inhibiting or delaying hair loss in human scalp, as well as cosmetic and pharmaceutical compositions suitable for such use: wherein :R 1 and R 2 together form a double bond, or R 1 and R 2 together form a cyclopropyl group; R 3 , R 4 same or different, and independently selected from hydrogen, methyl, or R 3 and R 4 together form a double bond; R 5 , R 6 the same or different, and independently selected from hydrogen, methyl; or R 5 and R 6 together form a double bond, or R 5 and R 6 together form a cyclopropyl group; R 7 = methyl or ethyl; R 8 = hydrogen or methyl.

Description

field of invention [0001] The present invention relates to the use of compounds for promoting human hair growth and / or inhibiting or delaying hair loss, and compositions for such use comprising these compounds as active ingredients. current technology [0002] The term sandalwood refers to a type of wood from trees of the genus Santalum. Sandalwood essential oil is usually extracted by steam distillation of wood from mature sandalwood trees and is a well-known and valuable ingredient of perfumes. [0003] Among its many different uses in the field of cosmetics, mainly in connection with its valuable fragrance, sandalwood oil is also the subject of patent publications on medicinal and empirical preparations for many different uses, including the general treatment of hair loss and dandruff, Such as, for example, patent publication CN1075250A describes a medicinal extract that is actually defined as a traditional Chinese medicine, including flower buds of magnolia, rose flower...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/34A61Q7/00
CPCA61Q5/02A61Q7/00A61K8/34A61K31/045A61P17/14A61K9/0014A61P17/00
Inventor 拉尔夫·保斯杰里米·谢雷特汉斯·哈特S·巴罗尼
Owner GIULIANI SPA
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