Micro-quantitative sampling system for biochip

A quantitative sampling and biochip technology, applied in sampling devices and other directions, can solve the problems of longer sample time, easy clogging of filter membranes, and crushed red blood cells, and achieves simple structure, sufficient blood filtration, and good stability.

Pending Publication Date: 2019-01-18
HUNAN LEGEND AI CHIP BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In the above-mentioned vertical blood filtration structure, since the red blood cells stay in the first chamber and will deposit on the filter membrane at the bottom of the first chamber, the concentration of red blood cells in the first chamber becomes higher and higher as the blood filtration progresses , so it is easy to block the filter membrane and cause insufficient blood filtration, the time required to filter a unit of sample becomes longer, the efficiency is reduced, and the red blood cells may even be crushed, resulting in sample failure

Method used

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  • Micro-quantitative sampling system for biochip

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Embodiment Construction

[0037] Such as figure 1 As shown, the biochip microquantitative sampling system includes a quantitative tube 4, and the bottom of the quantitative tube 4 offers a sample outlet 402; it also includes a housing 1, an air blowing unit 6, a camera unit 8 and a controller 9, and the housing 1 is provided with an installation through hole 105, the lower section of the quantitative tube 4 extends into the installation through hole 105, and the air blowing hole 106 connecting the air outlet of the blowing unit 6 and the lower section of the quantitative tube 4 is set on the side wall of the housing 1, and the lower section of the quantitative tube 4 and the installation through hole 105 The air passage 7 communicating with the blowing through hole 106 and the outer wall of the sample outlet 402 is formed between them; the sample outlet 402 is located within the field of view of the imaging unit 8, and the imaging unit 8 and the blowing unit 6 are electrically connected to the controlle...

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Abstract

The invention discloses a micro-quantitative sampling system for a biochip, which comprises a quantitative tube; a sample outlet is formed at the bottom of the quantitative tube. The micro-quantitative sampling system for a biochip further comprises a casing, a blowing unit, a camera shooting unit and a controller. A mounting through hole is formed in the casing; the lower section of the quantitative tube stretches to the mounting through hole; a blowing through hole is formed in the side wall of the casing for communicating a gas outlet of the blowing unit and the lower section of the quantitative tube; a gas passing channel is formed between the lower section of the quantitative tube and the mounting through hole for communicating the blowing through hole and the outer wall of the sampleoutlet; the sample outlet is located in a field range of the camera shooting unit; the camera shooting unit and the blowing unit are both electrically connected with the controller; and the controller is used for calculating the volume of a liquid drop according to the image of the liquid drop and controlling the output quantity of the blowing unit according to the volume of the liquid drop. Themicro-quantitative sampling system for a biochip in the invention uses a liquid drop non-contact manner to blow the quantitative sample liquid drop adhered to and suspended to the sample outlet at thetail end of the quantitative tube to a biochip reactor so that the sample is not polluted, and the sample quantitative precision is high; meanwhile, the structure is simple, the cost is low; and theconstancy is good.

Description

technical field [0001] The invention belongs to the technical field of biochip detection, in particular to a biochip microquantitative sampling system. Background technique [0002] The existing trace liquid sampling structure includes a quantitative tube. When in use, the air in the quantitative tube is first removed, and a small amount of liquid is quantitatively drawn from a certain container to the quantitative tube by using the principle of negative pressure, and then the quantitative tube is shifted (moved or is to rotate) to the designated position, and then use the air to push the liquid out of the quantitative tube to achieve the purpose of sampling. [0003] Biochip technology has developed rapidly in the past 20 years, especially the rapid development of microfluidic technology, new material technology and artificial intelligence technology, making biochip technology gradually industrialized. [0004] In the tiny biochip, the liquid cannot be drawn from the botto...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/10
CPCG01N1/10
Inventor 邬鹏程杨恒伟向苏民
Owner HUNAN LEGEND AI CHIP BIOTECH CO LTD
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