Genome assembling method
A genome assembly and consistency technology, applied in the field of genome assembly, can solve problems such as indistinguishability, fragmentation of continuous sequence fragments, and many operation steps
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[0056] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.
[0057] Embodiments of the present invention, a genome assembly method, such as figure 1 shown, including the following steps:
[0058] S1, compare all known DNA sequence fragments with each other, and find all overlapping read pairs with similar overlapping regions; wherein, the known DNA sequences include anchor sequence fragment set A and random sequencing read set B; the set of anchor sequence fragments A includes: one of the sequence fragment set A1 intercepted from the DNA sequence, the sequence fragment set A2 that has been assembled, and the read segment set A3 selected from random sequencing reads, or Several collections; said comparing all known DNA sequence fragments to each other, including comparing all anchor sequence fragments to all sequencing reads to each other, comparing all sequencing reads to each other, or comparing all T...
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