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Shandogen compound traditional Chinese medicine toothpaste and preparation method thereof

A technology of compound traditional Chinese medicine and mountain bean root, applied in dentistry, drug combination, pharmaceutical formula and other directions, can solve the problem of reducing the concentration of active ingredients in toothpaste, and achieve the effects of reducing toxicity, easy extraction and relieving rhinitis

Active Publication Date: 2021-05-11
缪剑华 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Toothpaste in the prior art basically uses paste, because a large amount of auxiliary materials will be added in the process of preparing toothpaste, which will greatly reduce the concentration of active ingredients in toothpaste. Compared with direct administration, it is very difficult to use a toothbrush to relieve oral ulcers. of

Method used

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  • Shandogen compound traditional Chinese medicine toothpaste and preparation method thereof
  • Shandogen compound traditional Chinese medicine toothpaste and preparation method thereof
  • Shandogen compound traditional Chinese medicine toothpaste and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] S1, get 10 parts of mountain bean root in parts by weight, 8 parts of Huoxiang, 8 parts of Peilan, 8 parts of mountain silver flower, 1 part of magnolia, 1 part of cornus and 1 part of cohosh, cut into small sections, mix, and Dry fry at 100°C for 25 minutes, take it out and grind it into powder, pass through a 60-mesh fine sieve to obtain a mixed powder, add 1 part by weight of menthol and 1 part of Panax notoginseng powder to the mixed powder, and stir evenly. To obtain the Chinese medicine component mixture, add 80% ethanol twice its total weight as an extractant to the Chinese medicine component mixture, stir at 50° C. for 30 min, filter to obtain the first filtrate and the first filter residue, and add the second filter residue to the first filter residue. 80% ethanol with 2 times the weight of a filter residue is used as an extractant, continue to stir at 50°C for 30min, filter to obtain the second filtrate and the second filter residue, combine the first filtrate ...

Embodiment 2

[0039] S1, get 30 parts of mountain bean root in parts by weight, 15 parts of Huoxiang, 15 parts of Peilan, 15 parts of Sanyinhua, 3 parts of magnolia, 3 parts of cornus and 3 parts of cohosh, cut into small sections, mix, and Dry fry at 150°C for 25 minutes, take it out and grind it into powder, pass through an 80-mesh fine sieve to obtain a mixed powder, add 3 parts by weight of menthol and 3 parts of Panax notoginseng powder to the mixed powder, and stir evenly. To obtain the Chinese medicine component mixture, add 80% ethanol twice its total weight to the Chinese medicine component mixture as an extractant, stir at 75° C. for 60 min, filter to obtain the first filtrate and the first filter residue, and add the second filter residue to the first filter residue. 80% ethanol with 2 times the weight of a filter residue is used as an extractant, continue to stir at 75°C for 60min, filter to obtain the second filtrate and the second filter residue, combine the first filtrate and ...

Embodiment 3

[0048] S1, get 25 parts of mountain bean root in parts by weight, 20 parts of Huoxiang, 10 parts of Perrin, 10 parts of Sanyinhua, 2 parts of Magnolia magnolia, 2 parts of cornus and 2 parts of Cimicifuga, cut into small sections, mix, and Dry fry at 100°C for 25 minutes, take it out and grind it into powder, pass through a 70-mesh fine sieve to obtain a mixed powder, add 2 parts by weight of menthol and 2 parts of Panax notoginseng powder to the mixed powder, and stir evenly. To obtain the Chinese medicine component mixture, add 80% ethanol twice its total weight as an extractant to the Chinese medicine component mixture, stir at 60° C. for 50 min, filter to obtain the first filtrate and the first filter residue, and add the second filter residue to the first filter residue. 80% ethanol with 2 times the weight of a filter residue is used as an extractant, continue to stir at 60°C for 50min, filter to obtain the second filtrate and the second filter residue, combine the first f...

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Abstract

The invention discloses a mountain bean root compound traditional Chinese medicine toothpaste and a preparation method thereof, comprising: Chinese medicine components, amorphous silicon dioxide, sorbitol, sodium lauroyl sarcosinate, sodium hydroxymethylcellulose, p-hydroxybenzoic acid Esters, natural xylitol, thickeners, adhesives; Among them, the traditional Chinese medicine components include: mountain bean root, ageratum, perrin, mountain silver flower, notoginseng powder, menthol, magnolia, cornus, cohosh . The preparation method is obtained by mixing the above-mentioned traditional Chinese medicine components after pretreatment, extracting, mixing with auxiliary materials and evenly stirring. The present invention can not only treat oral ulcers but also effectively alleviate the symptoms of rhinitis. The method of high-temperature stir-frying not only makes it easier to extract the beneficial components of traditional Chinese medicine, but also reduces the toxicity of the root extract. The filter residue extracted from traditional Chinese medicine is used CO 2 The supercritical fluid is re-extracted, and it is made into a paste combination of popping beads and toothpaste to effectively increase the concentration of the drug when brushing teeth and greatly enhance the therapeutic effect of oral ulcers.

Description

technical field [0001] The invention relates to the field of toothpaste. More specifically, the present invention relates to the mountain bean root compound traditional Chinese medicine toothpaste and its preparation method. Background technique [0002] Shandou root is a traditional Chinese medicinal material. It has the functions of clearing away heat, detoxifying, reducing swelling, relieving pain and relieving sore throat, especially in terms of clearing away heat, reducing swelling and treating swollen gums. Coptis chinensis and raw gypsum are equally used for purging fire. [0003] Toothpaste in the prior art basically uses paste, because a large amount of auxiliary materials will be added in the process of preparing toothpaste, which will greatly reduce the concentration of active ingredients in toothpaste. Compared with direct administration, it is very difficult to use a toothbrush to relieve oral ulcers. of. [0004] Due to the large amount of matrine contained ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/34A61K36/71A61K36/489A61Q11/00A61P1/02A61P11/02C08B37/04A61K31/045
CPCA61K8/34A61K31/045A61K36/258A61K36/28A61K36/355A61K36/40A61K36/489A61K36/532A61K36/575A61K36/71A61K2800/56A61K2800/5922A61K2800/805A61K2800/95A61Q11/00A61K8/9789A61P1/02A61P11/02C08B37/0084A61K2300/00Y02P20/54
Inventor 缪剑华王硕龚小妹欧春丽周小雷莫单丹宋志军
Owner 缪剑华
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