Pharmaceutical squeezing granulator realizing uniform granularity

A technology of granulation and granulation machine, applied in the direction of raw material extrusion granulation, etc., can solve the problems of poor effect and uneven hardness of drug granules, and achieve the effect of good compression effect, good hardness uniformity, and uniform acceptance

Inactive Publication Date: 2019-01-04
华蓥市铜堡初级中学
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the defects of inhomogeneous hardness and poor effect of the above-mentioned prepared drug granules, the purpose of the present invention is to provide an extrusion granulator with uniform particle size for pharmaceutical use. The setting of the driving mechanism and the briquetting block on the upper part of the chamber, each briquetting block has a small area, and the processing is uniform, and the prepared pellets have good hardness uniformity and a good pressing effect.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical squeezing granulator realizing uniform granularity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Such as figure 1 As shown, a pharmaceutical extrusion granulator with uniform particle size includes a box body, and a collecting hopper is arranged on the upper part of the box body, and the bottom of the collecting hopper is divided into a plurality of pressing chambers by a plurality of partitions, The bottom of each of the pressing chambers is provided with a plurality of through holes, the top of each of the pressing chambers is provided with a driving mechanism, and the bottom of each of the driving mechanisms is provided with a briquetting, the bottom of the pressing chamber is provided with a cutting mechanism, the lower part of the box is provided with a pushing mechanism, the top of the box is provided with a plurality of feeding ports, and the box on the opposite side of the pushing mechanism A discharge port is provided on the side wall of the body, a sealed door is provided on the discharge port, and a controller is provided on the outer wall of the box.

...

Embodiment 2

[0021] Based on Example 1, such as figure 1 As shown, a filter screen is provided under the pushing mechanism in the box, a slag discharge pipe is provided at the bottom of the box, and a valve is provided on the slag discharge pipe.

[0022] The filter is set so that the small particle impurities in the drug granulation pass through the filter, fall to the bottom of the box, and are discharged from the slag discharge pipe at the bottom of the box. The pushing mechanism pushes the material back and forth on the filter to prevent the filter from clogging.

Embodiment 3

[0024] Based on Example 1, such as figure 1 As shown, the pushing mechanism includes a telescopic rod positioned above the filter net, a push plate positioned at one end of the telescopic rod and a second motor positioned at the other end of the telescopic rod, and the other end of the telescopic rod extends to outside of the box.

[0025] The second motor drives the telescopic rod to expand and contract back and forth, and at the same time drives the push plate to push the material back and forth to prevent drug granulation from clogging.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a pharmaceutical squeezing granulator realizing uniform granularity, and belongs to the technical field of medical equipment. The squeezing granulator comprises a tank, whereina collecting hopper is arranged at the upper part in the tank, the bottom of the collecting hopper is divided into a plurality of pressing cavities through a plurality of partitions, a plurality of through holes are formed in the bottom of each pressing cavity, a driving mechanism is arranged above each pressing cavity, a pressing block matched with the corresponding pressing cavity is arranged at the bottom of each driving mechanism, and a cutting mechanism is arranged below bottoms of the pressing cavities; a pushing mechanism is arranged at the lower part of the tank, a plurality of feeding ports are formed in the top of the tank, a discharging port is formed in the side wall, opposite to the pushing mechanism, of the tank, a sealing door is arranged at the discharging port, and a controller is arranged on the outer wall of the tank. By means of the plurality of pressing cavities as well as the driving mechanisms arranged above the pressing cavities and the pressing blocks, each pressing block has small area and uniform stress, and the prepared pharmaceutical particles have good hardness uniformity and good pressing effect.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to an extrusion granulator with uniform particle size for pharmaceutical use. Background technique [0002] Pharmaceutical engineering is an engineering major that intersects chemistry, pharmacy (Chinese pharmacy) and engineering, with the goal of cultivating talents engaged in pharmaceutical manufacturing, new technology, new equipment, and new variety development, amplification, and design. This name officially appeared in the undergraduate professional catalog of the Ministry of Education in 1998. Although the name of the pharmaceutical engineering major is new, its emergence is not entirely new from the perspective of discipline evolution, it is a continuation of similar majors, and it is also a product of the development of China's science and technology to a certain period. Drugs refer to chemical substances that can affect the physiological, biochemical and patholo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01J2/20
CPCB01J2/20
Inventor 杨小华
Owner 华蓥市铜堡初级中学
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap