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Anti-adhesion hernia tablet with analgesic effect and preparation method thereof

An anti-adhesion and hernia sheet technology, applied in the medical field, can solve the problems of chronic pain and adhesion in patients, and achieve the effects of biocompatibility, degradability and good anti-adhesion effect.

Inactive Publication Date: 2019-01-04
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The main purpose of the present invention is to provide an anti-adhesion hernia sheet with analgesic effect and its preparation method, aiming to solve the problem of adhesion and chronic pain caused by the existing hernia sheet

Method used

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  • Anti-adhesion hernia tablet with analgesic effect and preparation method thereof
  • Anti-adhesion hernia tablet with analgesic effect and preparation method thereof
  • Anti-adhesion hernia tablet with analgesic effect and preparation method thereof

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Embodiment Construction

[0017] In order to make the purpose, features and advantages of the present invention more obvious and understandable, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described The embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making creative efforts belong to the protection scope of the present invention.

[0018] The hernia patches currently used in the market are mainly non-absorbable polyester patches, polypropylene patches, and expanded polytetrafluoroethylene patches, which cannot be degraded and absorbed in the body, and require a second operation to remove them. There are also obvious side effects of tablets: it is easy to produce adhesio...

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Abstract

The invention discloses an anti-adhesion hernia tablet with an analgesic effect and a preparation method thereof, and provides an anti-adhesion hernia tablet with an analgesic effect for solving the problem that existing hernia tablets can cause adhesion and chronic pain to patients. The hernia tablet is composed of a hernia tablet substrate, an electrospun nanofiber membrane wrapping the hernia tablet substrate and microspheres wrapped in the electrospun nanofiber membrane, and the electrospun nanofiber membrane on the surface of the hernia tablet and the the microspheres are made of a PLGA material which has degradability and biocompatibility and also has a good anti-adhesion effect; meanwhile, a high-penetrating anesthetic, namely tetracaine hydrochloride is embedded in the microsphereson the surface of the hernia tablet, so that the hernia tablet also has an analgesic effect. In summary, the hernia tablet can solve the problem that existing hernia tablets can cause adhesion and chronic pain to patients. The invention also provides a preparation method of the hernia tablet.

Description

technical field [0001] The invention relates to the field of medical technology, and more specifically relates to an anti-adhesion hernia sheet with analgesic effect and a preparation method thereof. Background technique [0002] At present, the hernia patches used in the market are mainly non-absorbable polyester patches, polypropylene patches, and expanded polytetrafluoroethylene patches, which have two obvious side effects: easy to produce adhesions and related inflammation, and there will be obvious postoperative Foreign body sensation; patients will have long-term discomfort, and severe cases will also have chronic pain. Therefore, it is urgent to provide an anti-adhesion hernia sheet with analgesic effect. Contents of the invention [0003] The main purpose of the present invention is to provide an anti-adhesion hernia sheet with analgesic effect and a preparation method thereof, aiming at solving the problem that the existing hernia sheet causes adhesion and chroni...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/16A61L31/14A61L31/06
CPCA61L31/16A61L31/06A61L31/14A61L31/148A61L2300/216A61L2300/402A61L2300/622C08L67/04
Inventor 杨军政王鹏元林姣杜萍陶雪莲
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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