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Ointment for urticaria papulosa

A technique for urticaria and papular rash, which is applied in the field of ointment for treating papular urticaria to achieve the effects of reducing side effects, reducing skin irritation and improving pigmentation

Active Publication Date: 2018-12-28
闫玮钰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is an urgent need to provide a composition for skin, which can reduce the side effects of hydrocortisone butyrate and solve the problem of pigmentation in a targeted manner

Method used

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  • Ointment for urticaria papulosa

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] An ointment for papular urticaria, comprising 1 part of hydrocortisone butyrate, 20 parts of paeonol, 60 parts of glycerin, 20 parts of propylene glycol, 145 parts of vaseline, and 95 parts of stearyl alcohol in parts by weight , 95 parts of liquid paraffin, 20 parts of Pingpingjia O2, 1.5 parts of citric acid, 0.5 parts of sodium citrate, and 568 parts of purified water.

[0026] Accurately measure according to the above proportions, the preparation method of the ointment is as follows: (1) oil phase preparation: mix stearyl alcohol, vaseline, and liquid paraffin, heat and melt to form a liquid, and keep the temperature at 75°C; (2) water phase preparation: glycerin , Pingping plus O, propylene glycol, citric acid, sodium citrate, and purified water are mixed and heated, and the temperature is kept at 75°C; (3) phase combination: slowly add the oil phase prepared in step (1) to step (2) In the prepared water phase, add it while stirring. When the temperature drops to 6...

Embodiment 2

[0028] An ointment for papular urticaria, comprising 1.5 parts of hydrocortisone butyrate, 23 parts of paeonol, 63 parts of glycerin, 25 parts of propylene glycol, 150 parts of vaseline, and 100 parts of stearyl alcohol in parts by weight , 100 parts of liquid paraffin, 25 parts of Pingpingjia O2, 2 parts of citric acid, 0.7 parts of sodium citrate, and 570 parts of purified water.

[0029] Accurately measure according to the above proportions, the preparation method of the ointment is as follows: (1) oil phase preparation: mix stearyl alcohol, vaseline, and liquid paraffin, heat and melt to form a liquid, and keep the temperature at 85°C; (2) water phase preparation: glycerin , Pingping plus O, propylene glycol, citric acid, sodium citrate, and purified water are mixed and heated, and the temperature is kept at 85°C; (3) phase combination: slowly add the oil phase prepared in step (1) to step (2) Add to the prepared water phase while stirring. When the temperature drops to 65...

Embodiment 3

[0031] An ointment for papular urticaria, comprising 2 parts by weight of hydrocortisone butyrate, 26 parts of paeonol, 65 parts of glycerin, 30 parts of propylene glycol, 155 parts of vaseline, and 105 parts of stearyl alcohol , 105 parts of liquid paraffin, 30 parts of Pingpingjia O, 4.5 parts of citric acid, 1 part of sodium citrate, and 574.5 parts of purified water.

[0032] Accurately measure according to the above proportions, the preparation method of the ointment is as follows: (1) oil phase preparation: mix stearyl alcohol, vaseline, and liquid paraffin, heat and melt to form a liquid, and keep the temperature at 80°C; (2) water phase preparation: glycerin , Pingping plus O, propylene glycol, citric acid, sodium citrate, and purified water are mixed and heated, and the temperature is kept at 80°C; (3) phase combination: slowly add the oil phase prepared in step (1) to step (2) Add to the prepared water phase while stirring. When the temperature drops to 63°C, add the...

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Abstract

The invention discloses an ointment for urticaria papulosa. The ointment comprises hydrocortisone butyrate as an active component, and further comprises paeonol as the active component, namely, the ointment comprises the following components in parts by weight: 1.5 parts of hydrocortisone butyrate, 23 parts of paeonol and 1005-1070.5 parts of an ointment substrate, wherein the ointment substrate comprises 60-65 parts of glycerinum, 20-30 parts of propylene glycol, 145-155 parts of vaseline, 95-105 parts of octadecanol, 95-105 parts of liquid paraffin, 20-30 parts of peregal O, 1.5-4.5 parts ofcitric acid, 0.5-1 part of sodium citrate and 568-574.5 parts of purified water. With the addition of paeonol, side effects of hydrocortisone butyrate can be reduced, irritation to skin can be reduced, and remarkable effects of etch relieving, pain relieving and swelling elimination can be achieved; chromatosis can be remarkably alleviated, and meanwhile, paeonol has a mosquito and insect expelling effect because of the special smell, and thus secondary biting allergy can be reduced; and the prepared ointment is free of preservative but has a preservation effect meeting standards.

Description

technical field [0001] The invention relates to an ointment for treating papular urticaria, in particular to an ointment containing hydrocortisone butyrate and paeonol. Background technique [0002] Papular urticaria is a disease named after its symptoms. It is also known as urticarial moss and baby moss. It is a delayed hypersensitivity skin disease related to insect bites. It is more common in infants and children. On the trunk, it is more common in spring, summer and autumn. The disease is characterized by round, oval or spindle-shaped red wheal-like papules with blisters or bullae on the top and small pit marks bitten by blood-sucking insects. There is no redness around. The number is indefinite, scattered distribution, also clustered but not fused, due to severe itching and scratching and skin damage secondary to impetigo, boils and other infectious skin diseases. The etiology is related to exogenous allergic reactions to bites of bedbugs, fleas, lice, mites, mosquitoe...

Claims

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Application Information

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IPC IPC(8): A61K31/573A61K31/12A61K9/06A61P17/00A61P37/08A61P17/02A61P17/04A61P29/00
CPCA61K9/0014A61K9/06A61K31/12A61K31/573A61K47/10A61P17/00A61P17/02A61P17/04A61P29/00A61P37/08A61K2300/00
Inventor 闫玮钰
Owner 闫玮钰
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