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Hydrogel skin wound dressing capable of resisting bacteria and promoting healing and preparation method of hydrogel skin wound dressing

A skin wound and hydrogel technology, applied in medical science, bandages, etc., can solve the problems of wasted dressing, non-antibacterial, inconvenient use process, etc., and achieve the effects of convenient use, good antibacterial and anti-inflammatory, and high antibacterial efficiency.

Inactive Publication Date: 2018-12-21
SICHUAN INST OF ATOMIC ENERGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the liquid dressing is in a liquid state, and it is inconvenient to use. It is a smearing method, which is easy to cause waste of the dressing. At the same time, the dressing does not have antibacterial properties. It is mainly used for wound healing in the later stage of trauma repair and to reduce the generation of scars and hyperplasia.

Method used

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  • Hydrogel skin wound dressing capable of resisting bacteria and promoting healing and preparation method of hydrogel skin wound dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] This embodiment provides an antibacterial and healing-promoting hydrogel skin wound dressing, a kind of antibacterial and healing-promoting hydrogel skin wound dressing, which consists of the following components in mass percentage:

[0035] Polyvinyl alcohol: 13%

[0036] Sodium alginate: 2%

[0037] Small molecule collagen peptide: 0.6%

[0038] Low Molecular Weight Hyaluronic Acid: 0.4%

[0039] Coptisine: 1.5%

[0040] Menthol: 0.5%

[0041] Deionized water: 82%;

[0042]Among the above components, coptisine is the extract of the Chinese herbal medicine Coptis Rhizoma, and menthol is the extract of the Chinese herbal medicine Peppermint.

Embodiment 2

[0044] This embodiment provides an antibacterial and healing-promoting hydrogel skin wound dressing, a kind of antibacterial and healing-promoting hydrogel skin wound dressing, which consists of the following components in mass percentage:

[0045] Polyvinyl alcohol: 11%

[0046] Sodium alginate: 1%

[0047] Small molecule collagen peptide: 0.6%

[0048] Low Molecular Weight Hyaluronic Acid: 0.4%

[0049] Angelica dahurica extract: 0.8%

[0050] Menthol: 0.2%

[0051] Distilled water: 86%;

[0052] Among the above components, the extract of Angelica dahurica is the total extract of the Chinese herbal medicine Angelica dahurica, and menthol is the extract of the Chinese herbal medicine Peppermint.

Embodiment 3

[0054] This embodiment provides an antibacterial and healing-promoting hydrogel dressing, which consists of the following components in mass percentage:

[0055] Polyvinyl alcohol: 10%

[0056] Sodium carboxymethyl cellulose: 2%

[0057] Small molecule collagen peptide: 0.5%

[0058] Low Molecular Weight Hyaluronic Acid: 0.4%

[0059] Small molecule silk peptide: 0.1%

[0060] Angelica dahurica extract: 0.8%

[0061] Menthol: 0.2%

[0062] Deionized water: 86%;

[0063] Among the above components, the Angelica dahurica extract is the root extract of the Chinese herbal medicine Angelica dahurica, and the menthol is the extract of the Chinese herbal medicine Peppermint.

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Abstract

The invention discloses a hydrogel skin wound dressing capable of resisting bacteria and promoting healing and a preparation method of the hydrogel skin wound dressing. The dressing comprises the following components: 10-15% of water-soluble macromolecular compounds, 0.1-5% of Chinese herbal medicine extracts, 0.1-1% of natural moisturizing and healing promoting materials, and the balance of water, wherein the natural moisturizing and healing promoting materials are selected from at least one kind of micromolecule collagen peptides, low-molecular weight hyaluronic acid and micromolecule natural silk peptides. According to the hydrogel skin wound dressing disclosed by the invention, Chinese herbal medicines which have the functions of resisting bacteria, diminishing inflammation, promotingtissue regeneration and removing necrotic tissues and the natural moisturizing and healing promoting materials are compounded and are in combined use to have a synergistic effect, so that the compatibility of the Chinese herbal medicines and the natural moisturizing and healing promoting materials with a hydrogel basal body is improved; the hydrogel skin wound dressing is slowly released and deeply infiltrates into skin, so that absorption of medicines and nutrient contents is promoted, and the healing of wounds is accelerated; besides, the hydrogel dressing disclosed by the invention has favorable bacterium resistance, high water absorption, favorable transparency and favorable healing promoting effects; the product is pure, and the technology is simple and convenient; the hydrogel skin wound dressing is especially suitable for wound healing of the skin, and can effectively promote healing of a II degree burn wound.

Description

technical field [0001] The invention relates to a medical wound dressing, in particular to an antibacterial and healing-promoting hydrogel skin wound dressing and a preparation method thereof, belonging to the field of biomedical materials. Background technique [0002] Medical wound dressings are an essential and important medical product in wound care in modern society. In order to improve the level of wound management, the development and application of medical dressings has attracted widespread attention in the world's medical and health fields. The field of medical dressing design has formed the characteristics of high-efficiency materials, high-efficiency products and high-efficiency care, which represents the development direction of medical dressings. [0003] The wet wound healing theory believes that a moist environment is more conducive to wound healing. Therefore, hydrogel dressings have shown greater advantages in wound healing. At the same time, hydrogel dressi...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0038A61L26/0066A61L26/008A61L2300/236A61L2300/252A61L2300/30A61L2300/404A61L2300/41A61L2300/412A61L2300/45
Inventor 倪茂君彭朝荣陈竹平王静霞江力黄科刘思阳陈屿恒张晓彬孙俊芝
Owner SICHUAN INST OF ATOMIC ENERGY
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