A three-dimensional photoacoustic endoscope in a curved cavity based on the direction change of snake bone and its imaging method

Abstract

The invention discloses a snake-bone-turning-based bending cavity internal three-dimensional opto-acoustic endoscope and an imaging method thereof. The endoscope comprises an integral scanning head, asnake bone bending part, an insertion hose, a three-dimensional scanning part, a control handle and a joint part. An opto-acoustic scanning probe and an optical camera are integrated in the integralscanning head, the opto-acoustic probe achieves mechanical circular scanning and retracting through the three-dimensional scanning part, the snake bone bending part is connected with the integral scanning head and the insertion hose, under adjustment of the control handle, four-way bending of the integral scanning head is achieved, and the joint part is connected with a pulse laser and a main unit. According to the method, by means of snake bone turning, bending cavity internal three-dimensional opto-acoustic imaging under the guidance of video images is achieved. Accordingly, the snake-bone-turning-based bending cavity internal three-dimensional opto-acoustic imaging method and the endoscope thereof combine high-resolution opto-acoustic imaging with high-resolution optical imaging, and bymeans of snake bone turning, bending cavity internal surface high-definition video images and a three-dimensional structure, function and molecular images of cavity tissue are obtained.

Description

technical field [0001] The invention belongs to the technical field of medical endoscopes, and relates to a three-dimensional photoacoustic endoscope in a curved cavity based on snake bone direction change and an imaging method thereof. Background technique [0002] Medical endoscope is an instrument for inspection, diagnosis and treatment of human body cavity tissue. Existing endoscopes mainly include optical video endoscopes, ultrasonic endoscopes and optical coherence tomography endoscopes. Optical video endoscopy can provide high-definition imaging of the cavity tissue surface, but cannot observe the fault structure of cavity tissue, which limits its ability to diagnose diseases to a certain extent; ultrasonic endoscopy can obtain deep structural information of cavity tissue , but its imaging contrast is low and cannot reflect early lesions; optical coherence tomography endoscopy can image cavity sections through focused beams, and has high resolution, but its imaging d...

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Problems solved by technology

[0005] Patent No. CN 102078179 A proposes a three-dimensional electronic colonoscope system, which uses a multi-CCD array module to perform linear and rotating three-dimensional scanning of the colon, displays a panoramic three-dimensional image, and reconstructs the three-dimensional image of the colon, but This invention can only obtain the three-dimensional surface information of the colonic tract, but cannot obtain the tomographic information of the intestinal tissue; Patent No. CN 103462644 A proposes a photoacoustic endoscope, which detects the target tissue after absorbing the pulsed laser. The ultrasonic signal is analyzed, processed and imaged, and a photoacoustic image with higher contrast can be obtained. However, this invention does not combine a directional bending part, and cannot pass through the curved cavity independently, and has no optical camera, so the cavity cannot be observed intuitively. The high-definition image of the surface is not conducive to the doctor's diagnosis

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