Method for detecting five sweetening agents in electronic cigarette liquor through ultra-high performance liquid chromatography-tandem mass spectrum
An ultra-high performance liquid phase, tandem mass spectrometry technology, applied in the field of physical and chemical inspection of food additive residues, to achieve the effect of simple pretreatment method, good repeatability, and strong resistance to matrix interference
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
example 1
[0033] 1. Instruments and reagents:
[0034] The 5 sweeteners and methanol are all chromatographic grade reagents; they meet the requirements of first-grade water in GB / T 6682.
[0035] Waters TQD quadrupole tandem mass spectrometer; Swiss Mettler AE 163 electronic balance (sensitivity: 0.0001g).
[0036] 2. Sample handling:
[0037] Weigh 100 μL of sample into a 2.0 mL centrifuge tube; add 900 μL of ultrapure water and 25 mg of C18 powder, vortex for 5 minutes, and centrifuge at 8000 r / h for 5 minutes, then filter, and the filtrate is used as the sample solution to be tested in UPLC -MS / MS analysis;
[0038] 3. Prepare and mix the mixed standard working solution; see the summary of the invention for the preparation method, and will not repeat it here.
[0039] 4. UPLC-MS / MS determination 。
[0040]5. Calculation of measurement results: Quantitative analysis is carried out by external standard method, that is, the quantitative ion pair peak area of various sweetener s...
example 2
[0043] According to the method described in Example 1, another e-cigarette liquid sample was selected, and the content of acesulfame potassium in the sample was 1.80 mg / kg.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com