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In-vitro-input-controllable balloon capable of reducing ischemia reperfusion injury

A controllable technique of ischemia-reperfusion, which is applied in the direction of balloon-shaped catheters and catheters to achieve the effect of avoiding blood vessel damage and ischemia-reperfusion injury

Active Publication Date: 2018-12-07
湖南省人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its design purpose is mainly to exchange guide wires, measure pressure or take blood in coronary arteries. If it is used in the field of acute vascular occlusion, reperfusion injury cannot be avoided, so it is not used in the field of treatment of acute vascular infarction; Improve and innovate on the basis of the above-mentioned technology, and become a controllable ischemia-reperfusion balloon injected in vitro, which can reperfuse the ischemic area in a continuous and uninterrupted way and at the same time deploy the perfusate, so as to reduce the ischemia-reperfusion injury

Method used

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  • In-vitro-input-controllable balloon capable of reducing ischemia reperfusion injury
  • In-vitro-input-controllable balloon capable of reducing ischemia reperfusion injury

Examples

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Effect test

Embodiment 1

[0025] see figure 1 , 2 It can be seen that the extracorporeal input controllable balloon for reducing ischemia-reperfusion injury in this embodiment includes a gas punching interface 1, a hard push tube 2 (a metal push tube is used in this embodiment), a perfusion hose (including a proximal soft Tube 3 and distal hose 6), balloon 5, guide wire 7 and flow control components; the perfusion hose is a double-layer tube structure, and the metal push tube 2 has a first pressurized chamber 9, the inner part of the perfusion hose There is a second pressurized chamber 10 inside the layer pipe, and the two communicate with each other to form a complete pressurized chamber. The pressurized chamber can be realized based on the metal push tube and the inner wall of the perfusion hose, or can be realized by a separate conduit inside. Such as, the first pressurization chamber just adopts the lumen of metal pushing pipe 2 to realize, and the second pressurization chamber can adopt the lume...

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Abstract

The invention provides an in-vitro-input-controllable balloon capable of reducing an ischemia reperfusion injury, and relates to the field of interventional medical apparatuses and instruments. The in-vivo-flow-controllable balloon capable of reducing the ischemia reperfusion injury is composed of a gas charging port, a hard pushing tube, a proximal soft tube, a balloon body, a distal soft tube, aguide wire and a flow control part, wherein the flow control part is composed of an outer perfusion joint and a flow controller connected on the outer perfusion joint through a catheter; controllableperfusion flow is achieved in an in-vitro-input-controllable manner; after the balloon is inflated, the balloon is not released, the in-vitro-input-controllable reperfusion balloon is controlled through the outer perfusion joint at the distal end of the balloon body and the flow controlled connected on the outer perfusion joint through the catheter, prepared perfusion fluid can be used for beingslowly perfused into the distal end of an infarction region or an ischemic region, and therefore the ischemia reperfusion injury is avoided; the balloon only needs one time of expansion and release while the distal end is subjected to perfusion, and blood vessel injuring, plaque falling and the distal blood-vessel no-reflowing phenomenon can be reduced or avoided.

Description

Technical field: [0001] The invention relates to the field of interventional medical devices, in particular to a balloon for reducing ischemia-reperfusion injury used in acute blood vessel occlusion. Background technique: [0002] At present, acute vascular occlusive disease is the main cause of death in the Chinese population, including acute myocardial infarction, cerebral infarction, peripheral arterial vascular embolism, etc., patients with acute vascular occlusive disease, the preferred method is emergency interventional treatment to open the infarct-related blood vessels, and then Perfuse the infarcted area; however, in the process of emergency intervention, directly opening the occluded blood vessel will cause further damage, which is called ischemia-reperfusion injury, resulting in further damage to the organs in the infarcted area. [0003] The traditional method of interventional therapy for acute vascular occlusive diseases is to use intravascular guide wires an...

Claims

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Application Information

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IPC IPC(8): A61M25/10
CPCA61M25/1025A61M25/104A61M2025/1079A61M25/10181A61M25/10184
Inventor 曹彦谢娇张宇谭波宇陈华丽丘小英王长录何晋刘征宇潘宏伟郑昭芬
Owner 湖南省人民医院
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