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Application of pharmaceutical composition in preparation of medicine for preventing and treating Salmonella infection in laying hens

A composition, the technology of Salmonella, applied in the direction of drug combination, plant/algae/fungus/moss components, pharmaceutical formulations, etc., to protect liver cells, reduce egg-derived pollution, and enhance the body's immunity

Active Publication Date: 2021-05-04
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems existing in the prior art, the present invention provides the application of a safe, reliable, hormone-free, side-effect-free and drug-residue pharmaceutical composition for preventing and treating Salmonella infection in laying hens, which can be used to purify Salmonella in laying hens , reduce the horizontal transmission of Salmonella in chicken flocks and egg-derived contamination caused by potential endogenous displacement, improve egg quality, and effectively avoid food safety problems caused by egg-derived Salmonella contamination

Method used

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  • Application of pharmaceutical composition in preparation of medicine for preventing and treating Salmonella infection in laying hens
  • Application of pharmaceutical composition in preparation of medicine for preventing and treating Salmonella infection in laying hens
  • Application of pharmaceutical composition in preparation of medicine for preventing and treating Salmonella infection in laying hens

Examples

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Effect test

Embodiment 1

[0027] The formula of the pharmaceutical composition of the prevention and treatment of laying hen Salmonella infection of the present invention is:

[0028] 30 parts by weight of baicalin flavone, 20 parts by weight of L-lysine, and 30 parts by weight of L-arginine.

[0029] Wherein, the preparation method of Scutellaria baicalensis is:

[0030] (1) Extraction of Scutellaria baicalensis flavonoids: crush the decoction pieces of Scutellaria baicalensis, pass through an 80-mesh sieve, add 5 times the weight of medicinal materials and 50% dimethyl sulfoxide solution, extract twice at 40°C for 60 minutes each time, filter, and combine the filtrates, spare.

[0031] (2) Membrane separation: the filtrate obtained in step (1) is subjected to membrane separation, and the membrane separation conditions are: select 10nm inorganic ceramic membrane, flow rate is 1.5L / min, pressure 0.12MPa and feed liquid temperature 30°C, to obtain Scutellaria baicalensis Concentrate.

[0032] (3) Spr...

Embodiment 2

[0035] The formula of the pharmaceutical composition of the prevention and treatment of laying hen Salmonella infection of the present invention is:

[0036] 35 parts by weight of Scutellaria baicalensis, 30 parts by weight of L-lysine, and 35 parts by weight of L-arginine.

[0037] The preparation method of baicalin flavonoids is the same as in Example 1.

[0038]According to the prescription ratio, 35 kg of baicalin flavonoids, 30 kg of L-lysine and 35 kg of L-arginine were weighed, mixed evenly and subpackaged to obtain a pharmaceutical composition for preventing and treating Salmonella infection in laying hens.

Embodiment 3

[0040] The formula of the pharmaceutical composition of the prevention and treatment of laying hen Salmonella infection of the present invention is:

[0041] 30 parts by weight of baicalin flavone, 40 parts by weight of L-lysine, and 30 parts by weight of L-arginine.

[0042] The preparation method of baicalin flavonoids is the same as in Example 1.

[0043] According to the prescription ratio, 30 kg of baicalin flavonoids, 40 kg of L-lysine and 30 kg of L-arginine are weighed, mixed evenly and subpackaged to obtain a pharmaceutical composition for preventing and treating Salmonella infection in laying hens.

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Abstract

The invention provides the application of the pharmaceutical composition in the preparation of drugs for preventing and treating Salmonella infection in laying hens, improving the laying performance of laying hens, reducing the number of Salmonella carried by egg shells and egg contents, and improving the quality of eggs. The pharmaceutical composition The raw materials in the formula are calculated in parts by weight: 30-50 parts of Scutellaria baicalensis, 20-40 parts of L-lysine, and 30-50 parts of L-arginine. The pharmaceutical composition for the prevention and treatment of Salmonella infection in laying hens with the core of "regulation from the source" of the present invention has the characteristics of green safety and no tolerance. It can replace antibiotics and can not only effectively inhibit and kill Salmonella, but also regulate The immune defense of the body can reduce the horizontal transmission of Salmonella in chicken flocks and the egg-derived contamination caused by potential endogenous displacement, improve egg production performance and egg quality, and effectively avoid food safety problems caused by egg-derived Salmonella.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and specifically relates to the application of a pharmaceutical composition in the preparation of a drug for preventing and treating Salmonella infection in laying hens, more specifically, to the application of a pharmaceutical composition in preparing a drug for preventing and treating Salmonella infection in laying hens, improving the Application in laying performance of chickens, reducing the number of Salmonella carried by egg shells and egg contents, and improving egg quality. Background technique [0002] Food safety problems caused by foodborne pathogens have been paid more and more attention, among which, food safety problems caused by Salmonella are an important reason that has plagued the healthy development of the poultry industry for a long time. In the United States, large-scale egg recalls have brought Salmonella infection in eggs into the focus of food safety again. Sa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/198A61K36/539A61P31/04A61P1/00A61P37/04
CPCA61K31/198A61K36/539A61P1/00A61P31/04A61P37/04A61K2300/00
Inventor 崔东安王磊王胜义王慧王玲张景艳
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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