Preparation method of nanosilver-supported medical dressing

A nano-silver, weighing technology, used in medical science, absorbent pads, bandages, etc., can solve the problems of non-degradability, limited tensile strength, difficult to meet requirements, etc., and achieve good biocompatibility and antibacterial properties. No toxic side effects, less irritating effect

Inactive Publication Date: 2018-10-16
SUZHOU JONATHAN NEW MATERIALS TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above treatment methods are relatively mature, there are still the following deficiencies: (1) it is difficult for the drug to maintain an effective concentration in the wound for a long time, and it cannot stably and continuously exert the drug effect; Degradability, needs to be replaced every 3 days
In the initial stage of wound formation, a large amount of wound exudate flows out. The existing dressings on the market can generally meet the needs of low to medium exudate, but it is difficult to meet the demand for wounds or wounds with high exudate
Existing dressings have relatively poor ductility, and in special parts such as buttocks and joints, often due to limited tensile strength, they cannot provide good comfort

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] A preparation method of a medical dressing loaded with nano-silver, the method comprising the following steps: weighing by weight: 15 parts of polyester fiber, 30 parts of chitosan, 3 parts of lemon peel pectin, 12 parts of polyglycolic acid , 10 parts of didecyldimethyl ammonium chloride, 3 parts of pectin, 5 parts of sodium carboxymethyl cellulose, 3 parts of alginate, 10 parts of silver zirconium phosphate, 10 parts of nano silver, 10 parts of nano zinc oxide 20 parts, 10 parts of honey, 5 parts of sodium dehydroacetate, 3 parts of molybdenum dithiocarbamate and 30 parts of water; put the above raw materials in a high-speed mixer, and disperse them at high speed by ultrasonic; then pour the dispersed mixture into the film-making On the mould, scrape it flat, dry it fully, remove the film, and make the drug storage layer; finally, the prepared drug storage layer and the base cloth are bonded and compounded by adhesive, and the bonded composite material is bonded by a d...

Embodiment 2

[0013] A preparation method of a medical dressing loaded with nano-silver, the method comprising the following steps: weighing by weight: 20 parts of polyester fiber, 40 parts of chitosan, 10 parts of lemon peel pectin, 20 parts of polyglycolic acid , 14 parts of didecyldimethyl ammonium chloride, 10 parts of pectin, 10 parts of sodium carboxymethyl cellulose, 12 parts of alginate, 20 parts of silver zirconium phosphate, 20 parts of nano silver, 20 parts of nano zinc oxide , 20 parts of honey, 8 parts of sodium dehydroacetate, 10 parts of molybdenum dithiocarbamate and 40 parts of water; the above raw materials are placed in a high-speed mixer, and ultrasonically dispersed at high speed; then the dispersed mixture is poured into the film-making mold , flattened, and fully dried, stripped to obtain the drug storage layer; finally, the prepared drug storage layer and the base cloth were bonded and compounded by adhesive, and the bonded composite material was punched by a dense ne...

Embodiment 3

[0015] A preparation method of a medical dressing loaded with nano-silver, the method comprising the following steps: weighing by weight: 17 parts of polyester fiber, 35 parts of chitosan, 6 parts of lemon peel pectin, 16 parts of polyglycolic acid , 12 parts of didecyldimethyl ammonium chloride, 6 parts of pectin, 8 parts of sodium carboxymethyl cellulose, 8 parts of alginate, 15 parts of silver zirconium phosphate, 15 parts of nano silver, 15 parts of nano zinc oxide , 15 parts of honey, 6 parts of sodium dehydroacetate, 6 parts of molybdenum dithiocarbamate and 35 parts of water; place the above-mentioned raw materials in a high-speed mixer, and disperse at high speed by ultrasonic; then pour the dispersed mixture into the film-making mold , flattened, and fully dried, stripped to obtain the drug storage layer; finally, the prepared drug storage layer and the base cloth were bonded and compounded by adhesive, and the bonded composite material was punched by a dense needling ...

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PUM

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Abstract

The invention discloses a preparation method of a nanosilver-supported medical dressing. The nanosilver-supported medical dressing is prepared from the following components in parts by weight: 15 to 20 parts of polyester fiber, 30 to 40 parts of chitosan, 3 to 10 parts of lemon peel pectin, 12 to 20 parts of polyglycolic acid, 10 to 14 parts of didecyl dimethyl ammonium chloride, 3 to 10 parts ofpectin, 5 to 10 parts of sodium carboxymethylcellulose, 3 to 12 parts of alginate, 10 to 20 parts of zirconium phosphate-supported silver, 10 to 20 parts of nanosilver, 10 to 20 parts of nanoscale zinc oxide, 10 to 20 parts of honey, 5 to 8 parts of sodium dehydroacetate, 3 to 10 parts of molybdenum dithiocarbamate and 30 to 40 parts of water. The nanosilver-supported medical dressing prepared bythe method disclosed by the invention has the advantages of little irritation, no toxic and side effects, no relapse and good biocompatibility and antibacterial property.

Description

technical field [0001] The invention relates to a preparation method of a medical dressing loaded with nanometer silver. Background technique [0002] Difficulty in wound healing is a frequently encountered problem in plastic surgery. Clinically, the treatment of small wounds is mainly through active iodine disinfection, spraying human epidermal growth factor and other drugs, and finally covering with sterile gauze. For large wounds, skin grafts and skin flaps are mainly used. After surgical treatment, the surface is covered with Vaseline gauze, and finally covered with sterile gauze. Although the above treatment methods are relatively mature, there are still the following deficiencies: (1) it is difficult for the drug to maintain an effective concentration in the wound for a long time, and it cannot stably and continuously exert the drug effect; Degradability, need to be replaced every 3 days. Medical dressings are wound-wrapping supplies, medical materials used to cov...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/26A61L15/28A61L15/40A61L15/46
CPCA61L15/18A61L15/26A61L15/28A61L15/40A61L15/46A61L2300/104A61L2300/404C08L67/04C08L5/08C08L5/06C08L1/286C08L5/04
Inventor 吕少波李卓才李苏杨
Owner SUZHOU JONATHAN NEW MATERIALS TECH
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