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Formulation and method of use

A technology for preparations and edible oils, which are used in anti-inflammatory agents, pharmaceutical formulations, non-central pain relievers, etc.

Inactive Publication Date: 2018-09-28
ATP INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] While many treatments for inflammation are known, they all have limitations, especially in terms of broad-based efficacy

Method used

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  • Formulation and method of use
  • Formulation and method of use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0117] A combination of grapefruit oil (2.5%) and peppermint oil (7.5%) combined with safflower oil (45%), pomegranate seed oil (20%) and coconut oil (25%) was tested in preclinical trials in obesity preparation.

[0118] method

[0119] Before and during exercise, the test subjects took 2 ml of the liquid oil formulation orally. The subjects were interviewed immediately after taking the dose, and again after exercise (post-workout) and the answers were recorded.

[0120] result

[0121] Table 1

[0122]

[0123]

[0124] Further comments:

[0125] • Mouthfeel well tolerated both with and without emulsifier in 100% of subjects. One subject didn't like it but tolerated it and continued to use the product and asked for more. The subject explained that they had "acquired taste".

[0126] • 100% of subjects well tolerated the essential oils used for flavoring.

[0127] • Subjects reported increased arousal and perceived energy.

[0128] • Subjects anecdotally report...

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PUM

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Abstract

Provided is an orally administrable formulation comprising a flavour oil that includes menthol and / or limonene and an edible oil, in which both the flavour oil and the edible oil possess anti-inflammatory properties. Methods of using the aforementioned orally administrable formulation for decreasing and / or preventing an increase in body fat and / or body weight and the prevention and / or treatment ofan inflammatory disease, disorder or condition, including obesity, asthma and inflammatory bowel disease, are also provided. Also provided are methods of producing the aforementioned orally administrable formulation.

Description

technical field [0001] The present invention relates to anti-inflammatory and / or anti-obesity formulations and methods of treatment and / or use thereof. The formulations are useful in various cosmetic and / or therapeutic applications, such as enhancing weight loss and / or treating inflammation in such conditions including obesity, asthma and inflammatory bowel disease (IBD). Background technique [0002] The body can use many substrates (including carbohydrates, proteins, fats, ketones and alcohols) as fuel sources. In order to specifically support and / or encourage fat to be used as a primary fuel source, the body needs to overcome many hurdles. To this end, there is a hierarchical system that controls which fuel source is used first, and this is typically determined by substrate availability, hormonal profile, stress level, activity type and intensity, and signals from gustatory and olfactory sensations that predict substrate availability to control. [0003] Most fat burni...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K36/534A61K36/53A61K35/60A61K35/612A61K36/286A61K36/889A61K36/185A61K35/57A61K9/107A61P29/00A61P3/04
CPCA61K9/0095A61K35/57A61K35/60A61K35/612A61K36/185A61K36/286A61K36/53A61K36/534A61K36/752A61K36/889A61K47/44A23L27/12A23L33/115A61P3/04A61P29/00A61K2300/00A61K9/0053A61K36/28A23L27/13A23L33/12
Inventor M·莱格
Owner ATP INST
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