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Application of pachymic acid or pachymic acid derivative in preparing medicine for treating polycystic ovary syndrome and medicinal preparation

A polycystic ovary and pharmaceutical preparation technology, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as large side effects and poor therapeutic effects

Active Publication Date: 2018-09-18
XIAMEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] The purpose of the present invention is to provide a kind of pachymic acid or pachymic acid derivatives for the preparation of the application and the pharmaceutical preparations

Method used

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  • Application of pachymic acid or pachymic acid derivative in preparing medicine for treating polycystic ovary syndrome and medicinal preparation
  • Application of pachymic acid or pachymic acid derivative in preparing medicine for treating polycystic ovary syndrome and medicinal preparation
  • Application of pachymic acid or pachymic acid derivative in preparing medicine for treating polycystic ovary syndrome and medicinal preparation

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Embodiment Construction

[0023] Preferred embodiments of the present invention will be described in more detail below. Although preferred embodiments of the present invention are described below, it should be understood that the present invention can be embodied in various forms and should not be limited by the embodiments set forth herein.

[0024] In the present invention, relevant terms are defined as follows:

[0025] Pachylic acid (PA), a triterpenoid compound in Poria cocos and Ganoderma lucidum Chinese herbal medicine, is one of the main active ingredients of Poria cocos and plays an important role in various pharmacological effects. For example, the traditional Chinese medicine Daotan Pill, Qigong Pill and Dingjing Decoction all have the same vital Chinese medicine, that is, Poria cocos.

[0026] In the present invention, there is no special limitation on the source of pachymic acid, which can be obtained commercially or prepared according to various existing methods, including extraction and...

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Abstract

The invention relates to application of pachymic acid or pachymic acid derivative in preparing medicine for treating polycystic ovary syndrome and a medicinal preparation. The invention provides a newapplication of pachymic acid or a derivative thereof, which has a remarkably treatment effect for polycystic ovary syndrome, and does not have side effect. Pachymic acid is verified, by the embodiment of the invention, to be available in treating mice polycystic ovary syndrome, and can provide a new candidate medicine for treating polycystic ovary syndrome for clinic.

Description

technical field [0001] The invention relates to the field of treating polycystic ovary syndrome, in particular to the application and pharmaceutical preparation of pachymic acid or pachymic acid derivatives for preparing medicine for treating polycystic ovary syndrome. Background technique [0002] Polycystic ovary syndrome (polyeystie ovary syndrome, PCOS), also known as Stein-leventhal syndrome, is a common endocrine syndrome in women of childbearing age, which is caused by multiple genes, multiple genetic factors, and multiple environmental factors. A heterogeneous disease characterized by disorders of the ovarian function axis, menstrual disorders (oligomenorrhea or amenorrhea), persistent anovulation, infertility, insulin resistance, hyperinsulinemia, ovarian polycystic changes, and hyperandrogenism. According to a large number of clinical data, most researchers believe that the main pathogenesis of this disease is diet, genetics, mental and environmental factors, and i...

Claims

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Application Information

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IPC IPC(8): A61K31/575A61P15/08A61P5/00
CPCA61K31/575A61P5/00A61P15/08
Inventor 王海龙符贤佩
Owner XIAMEN UNIV
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