Composite probiotics capable of increasing survival rate of piglets

Abstract

The invention discloses composite probiotics capable of increasing the survival rate of piglets, and relates to the technical field of microorganisms. The composite probiotics consist of probiotics and avian immunoglobulin IgY. The composite probiotics can reduce the incidence rate of yellow dysentery, white dysentery, other intestinal bacterial loose bowels, and diarrhoea of piglets, increase thesurvival rate of the piglets, promote development of immune organs of the piglets, enhance the immunity and the disease resistance of the piglets, reduce the attack rate, complement intestinal probiotics, adjust intestinal flora environment of the piglets, strengthen the resistance of the piglets to environment stress, improve the chronicity and the stability of the health of piglet groups, protect the normal development of intestinal mucosae and intestinal villi, and improve the nutrient absorption capacity. When the avian immunoglobulin IgY is used, blood sampling is not needed, only eggs produced by immune hens need to be collected, so that antibodies can be obtained; and a small quantity of antigen immunity birds are used, a large quantity of specific IgY homogeneous in quality can beobtained, and the avian IgY and mammal immunoglobulin cannot generate a cross serologic reaction.

Description

Technical field: [0001] The invention relates to the technical field of microbes, in particular to a compound probiotic for improving the survival rate of piglets. Background technique: [0002] The growth stages of pigs are divided into piglets, nursery pigs and fattening pigs, but the piglet stage is most vulnerable to various pathogens, and it is the stage with the highest mortality rate in the life of the pig herd, accounting for about 80% of the mortality of the whole pig herd; piglets Because the autoimmune system is not fully developed and the disease resistance is poor, it is very easy to be infected with immunosuppressive diseases caused by swine fever and circovirus, as well as digestive system diseases such as piglet yellow and pullorum; The immunosuppressive disease caused by it has always been one of the main diseases that endanger the pig industry in China, and it is becoming more and more serious, especially for piglets, which is more harmful and causes higher...

AI Technical Summary

Problems solved by technology

[0002] The growth stages of pigs are divided into piglets, nursery pigs and fattening pigs, but the piglet stage is most vulnerable to various pathogens, and it is the stage with the highest mortality rate in the life of the pig herd, accounting for about 80% of the mortality of the whole pig herd; piglets Because the autoimmune system is not fully developed and the disease resistance is poor, it is very easy to be infected with immunosuppressive diseases caused by swine fever and circovirus, as well as digestive system diseases such as piglet yellow and pullorum; The immunosuppressive disease caused by it has always been one of the main diseases that endanger the pig industry in China, and it is becoming more and more serious, especially for piglets, which is more harmful and causes higher mortality, which has caused serious economic losses to the pig industry; After weaning, piglets change from eating breast milk to eating solid feed, which easily wears down the intestinal mucosa, causing the villi of the intestinal mucosa to atrophy, and the nutrients must be absorbed through the villi in the small intestine, so the nutrients cannot be well digested and absorbed , causing the fermentation of intestinal nutrients and disrupting the normal intestinal flora environment, often causing severe E. coli and Salmonella infections, resulting in intractable diarrhea; E. coli and Salmonella produce intestinal endotoxins during the metabolic process, which can easily further cause sepsis. exacerbated piglet mortality

[0003] At present, there are few medicines used in veterinary clinics to prevent and treat immunosuppressive diseases, and the effect is not ideal, so it is difficult to meet the clinical needs; antibiotics and sulfonamides are generally used to control diarrhea. Due to long-term abuse of antibiotics and sulfonamides, This leads to the development of drug resistance to many bacterial strains, which greatly increases the dosage of drugs and enhances the toxicity of liver and kidney, which not only increases the cost of drugs, but also increases the harm of antibiotic residues and side effects to the human body; Diarrhea diseases are also prevented and treated by traditional Chinese medicine preparations, but most of them are powders, with a strong smell and a large amount of medicine. It is difficult to give oral administration to piglets, and there are poor bioavailability, resulting in waste of medicinal materials and unsatisfactory treatment effects.