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Pharmaceutical composition for controlling infectious laryngotracheitis of chicken and preparation method and applications thereof

A composition and technology of tracheitis, applied in the field of pharmaceutical composition and its preparation for preventing and treating chicken infectious laryngotracheitis, can solve the problems of chicken growth rate and egg production rate decline, endangering human food safety, serious drug residues and other problems , to achieve the effects of less drug resistance, improved antiviral ability, and strong antibacterial and anti-inflammatory ability

Inactive Publication Date: 2018-07-24
绵阳市农业科学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This type of drug has a single target. Although it can achieve certain curative effect, its many disadvantages are becoming more and more obvious. For example, it is easy to produce drug resistance, which will cause serious drug residues in chickens, endanger human food safety, and easily reduce the growth rate of chickens. and egg production rate drop, resulting in economic losses, etc.

Method used

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  • Pharmaceutical composition for controlling infectious laryngotracheitis of chicken and preparation method and applications thereof

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preparation example Construction

[0036] In the second aspect, this embodiment also provides a method for preparing the above-mentioned pharmaceutical composition, which includes:

[0037] Step S1: In parts by weight, mix the shegan, dandelion and kuditin, mix with 70-80% alcohol solution according to the material-to-liquid ratio of 1:10-12, soak for 24 to 48 hours, separate and concentrate to obtain the medicinal solution;

[0038] Further, the temperature during immersion is 40-50°C.

[0039] Step S2: Mix the medicinal solution with alum, and after standing still, filter and concentrate to obtain an extract;

[0040] Furthermore, the relative density of the extract is 1.8~2.0g / cm 3 .

[0041] Step S3: The extract is mixed with borneol and ascorbic acid and dried.

[0042] Further, drying is a low-temperature freeze-drying method.

Embodiment 1

[0045] This embodiment provides a pharmaceutical composition for preventing and treating infectious laryngotracheitis in chickens, which includes:

[0046] 12 parts of shegan, 15 parts of dandelion, 2 parts of Kuditin, 8 parts of borneol, 2 parts of alum, 3 parts of ascorbic acid.

[0047] The preparation method of the pharmaceutical composition includes:

[0048] a. Mix shegan, dandelion and kuditin, mix with 80% ethanol solution according to the material-to-liquid ratio of 1:10, soak at 50℃ for 48h, separate and concentrate to obtain the medicinal solution;

[0049] b. Then mix the medicinal solution with alum, leave it still, filter and concentrate to obtain the extract, the relative density of which is 1.8g / cm 3 ;

[0050] c. Mix the extract with borneol and ascorbic acid and dry.

Embodiment 2

[0052] This embodiment provides a pharmaceutical composition for preventing and treating infectious laryngotracheitis in chickens, which includes:

[0053] Shegan was 15 parts, dandelion was 14 parts, Kuditin was 3 parts, borneol was 6 parts, alum was 4 parts, and ascorbic acid was 2 parts.

[0054] The preparation method of the pharmaceutical composition includes:

[0055] a. Mix shegan, dandelion and kuditin, mix with 75% ethanol solution according to the material-to-liquid ratio of 1:11, soak at 45°C for 32h, separate and concentrate to obtain the medicinal solution;

[0056] b. Then mix the medicinal solution with alum, leave it still, filter and concentrate to obtain the extract, the relative density of which is 1.9g / cm 3 ;

[0057] c. Mix the extract with borneol and ascorbic acid and dry.

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Abstract

The invention provides a pharmaceutical composition for controlling infectious laryngotracheitis of chicken and a preparation method and applications thereof, and belongs to the field of veterinary drugs. The pharmaceutical composition comprises following components in parts by weight: 12 to 17 parts of blackberry lily rhizome, 10 to 15 parts of dandelion, 2 to 7 parts of bunge corydalis herb, 3 to 8 parts of borneol, 2 to 9 parts of alum, and 1 to 3 parts of ascorbic acid. Through the cooperation among the raw materials, the antibacterial and anti-inflammation performance of the pharmaceutical composition is strong, the transmission of chicken infectious laryngotracheitis virus is inhibited, the disease resistance is enhanced, the antibody generation is promoted, the dead rate is reducedeffectively, the drug resistance is difficult to generate, and the curative effect is quick and excellent.

Description

Technical field [0001] The present invention relates to the field of veterinary medicine, in particular to a pharmaceutical composition for preventing and treating infectious laryngotracheitis in chickens, and a preparation method and application thereof. Background technique [0002] Infectious laryngotracheitis (ILT) is an acute, febrile, and highly contagious upper respiratory tract infection in chickens caused by Infectious laryngotracheitis virus (ILTV). Infected chickens manifest as respiratory Difficulties, coughing up bloody mucus, tracheal mucosal edema and hemorrhage, etc., and cause death of infected chickens and decrease in egg production of laying hens, causing serious economic losses to the chicken industry. [0003] ILT is widespread all over the world, seriously affecting the healthy development of the poultry industry. The disease was discovered in my country in the 1950s and it is now widespread, and it is one of the important diseases that harm the chicken indus...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P31/22A61K33/06A61K31/375A61K31/045
CPCA61K31/045A61K31/375A61K33/06A61K36/288A61K36/66A61K36/88A61K2236/333A61K2300/00
Inventor 王育伟康润敏岳华王志胜
Owner 绵阳市农业科学研究院
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