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Diagnostic test with lateral flow test strip

A technology for diagnostic tests and test strips, used in disease diagnosis, measurement devices, fluid controllers, etc., to solve problems such as peritoneal damage, high treatment costs, and loss of infusion lines/tubes

Inactive Publication Date: 2018-07-17
MOLOGIC LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Unfortunately, infection is the number one reason patients lose their freedom to use PD because infection causes damage to the peritoneum and loss of infusion lines / tubing
Treatment is expensive and surgery is required where online is lost

Method used

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  • Diagnostic test with lateral flow test strip
  • Diagnostic test with lateral flow test strip
  • Diagnostic test with lateral flow test strip

Examples

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Embodiment Construction

[0221] The following illustrates, by way of example only, the present disclosure for the testing of dialysate fluid for peritonitis infection, where the dialysate fluid is contained in or flows into a dialysate bag. It will be apparent that the diagnostic test devices, kits and methods herein can be used in conjunction with other fluids and other containers, and for testing of different substances and conditions.

[0222] A first embodiment of a diagnostic test device 10 according to the present disclosure is shown in Figures 2 to 5 , and includes an elongated housing 11 defining a test strip holder 12 containing a lateral flow test strip 13 . A fluid sampling chamber 14 is provided which is connected to the test strip holder 12 through an internal fluid opening. The long housing 11 is provided with a viewing window 16 which allows a portion of the lateral flow test strip 13 to be viewed and read.

[0223] Lateral flow test strip 13 can protrude into fluid sampling chamber ...

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Abstract

A diagnostic test apparatus comprises: an elongate housing defining a test strip holder containing a lateral flow test strip; a fluid sampling chamber provided with an opening connecting the fluid sampling chamber with the test strip holder; a viewing window in the elongate housing allowing reading of one or more portions of the lateral flow test strip; and a connector configured to couple the diagnostic test apparatus to a bulk source of fluid. The apparatus may be included in a kit of parts. The apparatus is useful for detecting peritonitis. The bulk source of fluid may be peritoneal dialysate. Various markers may be determined in the bulk source of fluid such as MMP8, IL-6, HNE, MMP2, MMP9, TIMP1, TIMP2, NGAL, A1AT, desmosine, fibrinogen, IL-8, calprotectin, fMLP, IL1 b, cystatin C, HSA, RBP4, SPD, MPO, sICAM and TNFa. Detection of the markers to indicate peritonitis may also inform treatment choices.

Description

technical field [0001] The present disclosure relates to diagnostic test devices and related kits. The present disclosure further relates to methods of testing fluids. In particular, the present disclosure discloses a diagnostic test device that can be used to test fluids. The present diagnostic test apparatus may find particular application in the testing of bulk sources of fluids. An example application is peritoneal dialysis fluid testing for infectious diseases such as peritonitis. Background technique [0002] Peritoneal dialysis (PD) is the preferred management method for patients with renal failure in a home setting, allowing patients to maintain a near normal life and routine. PD is a passive activity requiring multiple (typically 4) bag changes a day to remove toxins from the bloodstream. PD is an alternative to hemodialysis and involves using the peritoneum in the patient's abdominal cavity as an exchange membrane for exchanging substances with the blood. A ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5023B01L2200/026B01L2300/0663B01L2300/0672B01L2300/0825B01L2400/0406A61M1/1654A61M1/287G01N2800/06G01N2800/52C12Q1/37G01N33/558G01N2800/26G01N2800/7095G01N33/573G01N2333/5412G01N2333/96494G01N33/54388A61M2210/0625A61M2210/1017A61M2210/12G01N33/54306G01N33/6869
Inventor 吉塔·帕瑞克
Owner MOLOGIC LTD
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