Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for extracting proanthocyanidin A2 from peanut coat

A technology of peanut coat extract and proanthocyanidins, which is applied in the direction of organic chemistry, can solve the problems of high environmental protection pressure, the inability to regenerate silica gel completely, and the complex process, achieve strong antioxidant activity, promote sustainable development, and enhance added value. Effect

Inactive Publication Date: 2018-07-17
浙江天草生物科技股份有限公司
View PDF4 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent document CN201310314385.4 discloses a method for extracting proanthocyanidin A2 from litchi leaves. This method requires the use of a large amount of organic solvents. The silica gel used in the chromatographic column cannot be completely regenerated and needs to be replaced frequently, thus generating a large amount of solid-liquid waste , the pressure of environmental protection is high, and the process is relatively complicated, which is not conducive to large-scale production

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for extracting proanthocyanidin A2 from peanut coat
  • Method for extracting proanthocyanidin A2 from peanut coat
  • Method for extracting proanthocyanidin A2 from peanut coat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Add 8000 grams of deionized water to 1000 grams of peanut shell raw materials, heat to 60 °C, and extract for 2 hours; then add 8000 grams of deionized water, heat to 60 °C, and extract for 1.5 hours; combine the two extracts, filter, and reduce the filtrate Concentrate under pressure and dry in vacuum to obtain the extract of peanut shell with a yield of 15.7%.

Embodiment 2

[0030] Example 2: Add 16000 grams of deionized water to 1000 grams of peanut shell raw materials, heat to 60 ° C, and extract for 2 hours; then add 16000 grams of deionized water, heat to 60 ° C, and extract for 1.5 hours; combine the two extracts, After filtering, the filtrate was concentrated under reduced pressure and dried in vacuo to obtain the extract of peanut shell with a yield of 14.8%.

Embodiment 3

[0031] Example 3: Add 8000 grams of deionized water to 1000 grams of peanut shell raw materials, heat to 80 ° C, extract for 1 hour, then add 8000 grams of deionized water, heat to 80 ° C, extract for 1 hour, and combine the two extracts, After filtering, the filtrate was concentrated under reduced pressure and dried in vacuo to obtain the extract of peanut shell with a yield of 14.0%.

[0032] 2. Enrichment of proanthocyanidin A2 macroporous resin

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for extracting proanthocyanidin A2 from peanut coat, the method comprises the following steps: (1) using the peanut coat as a raw material, heating with water, extracting and filtering to obtain peanut coat extract; (2) first adsorbing the peanut coat extract by macroporous resin, pre-washing the macroporous resin with an alcohol solution as a pre-washing liquid, and desorbing by using an alcohol solution as a desorbing solution to obtain desorbed crude proanthocyanidin A2; and (3) finely separating the crude proanthocyanidin A2 by medium and low pressure preparative chromatography, after chromatographic separation, concentrating under reduced pressure and drying eluate to obtain the proanthocyanidin A2. The proanthocyanidin A2 obtained by the method has strong antioxidant activity, and the purity reaches 85% or more. The method is of great significance for promoting the deep processing and utilization of the peanut coat, enhancing the added value of peanut products and promoting the sustainable development of the industry.

Description

technical field [0001] The invention belongs to the field of separation and purification of natural product active substances, and in particular relates to a proanthocyanidin A2 with strong antioxidant activity and a preparation method thereof. Background technique [0002] Procyanidin is a general term for a class of flavonoids widely present in the plant kingdom, and is a polymer of flavan-3-ol or flavan-3,4-diol. In edible plants, proanthocyanidins are composed of (+)-catechin and (-)-epicatechin as constituent units, and form proanthocyanidin B class through B-type bonding, such as proanthocyanidin B2 shown in formula 1; Type A bonding forms proanthocyanidin A class, such as proanthocyanidin A2 shown in formula 2. According to the degree of polymerization, two, three and tetramers are usually called oligomer proanthocyanidins. Those above pentamers are called high polymers. Relevant studies have shown that proanthocyanidins have various biological functions, such as a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07D493/18
CPCC07D493/18
Inventor 李若鹏阎昊裘金明李大伟程勇邵云东
Owner 浙江天草生物科技股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com