Feed additive with liver-protection functions and preparation method thereof

A feed additive and liver function technology, which is applied in the field of feed additives with liver protection function and its preparation, can solve the problems of high addition cost, intolerant storage, unstable chemical properties of silymarin and the like, and achieves good mixing uniformity and low cost. , the effect of improving growth performance indicators

Inactive Publication Date: 2018-06-29
GUANGZHOU LEADER BIO TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The technical problems to be solved are silymarin's unstable chemical properties, intolerance to storage, high cost of addition and how to improve its application effect in animal feed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Preparation of a feed additive with hepatoprotective function:

[0029] 1. Step 1. Superfinely pulverize silymarin through a 200-mesh sieve for later use;

[0030] 2. Step 2, heating monoglyceride stearate to 85°C to melt it into a clear light yellow liquid;

[0031] 3. Step 3: Add 150 kg of silymarin prepared in step 1 through a vibrating sieve to 750 kg of 85°C heated and melted monoglyceride stearate, and stir at a high speed with scraping (60rpm) and high-speed stirring (2800rpm). Mix in a shear mixer for 45 minutes;

[0032] 4. Step 4: The mixture prepared in Step 3 is transported to the top of the cooling granulation tower through the heat preservation feed pump, and the mixture forms fine particles through the atomizer, and is rapidly cooled and solidified by the action of the cooling wind in the granulation tower to form a bead shape Small solid particles, separated and collected by automatic sedimentation or cyclone separator;

[0033] 5. Step 5. Collect the...

Embodiment 2

[0037] Preparation of a feed additive with hepatoprotective function:

[0038] 1. Step 1. Superfinely pulverize silymarin through a 200-mesh sieve for later use;

[0039] 2. Step 2, heating polyethylene glycol to 80°C to melt it into a clear colorless liquid;

[0040] 3. Step 3: Pass 100 kg of silymarin prepared in Step 1 through a vibrating sieve into 500 kg of polyethylene glycol 4000 heated and melted at 70°C, and stir under high-speed shear with scraping (100rpm) and high-speed stirring (2500rpm). Blend in a blender for 60 minutes;

[0041] 4. Step 4: The mixture prepared in Step 3 is transported to the top of the cooling granulation tower through the heat preservation feed pump, and the mixture forms fine particles through the atomizer, and is rapidly cooled and solidified by the action of the cooling wind in the granulation tower to form a bead shape Small solid particles, separated and collected by automatic sedimentation or cyclone separator;

[0042] 5. Step 5. Col...

Embodiment 3

[0045] Embodiment 3: storage stability experiment

[0046] Get 3 batches of samples of the feed additive of the present invention, each batch of samples is evenly mixed and divided into 6 bags, each bag is 20g, sealed and packaged in aluminum foil bags. The samples were sealed and packaged, placed indoors at room temperature, and the initial silymarin content (HPLC) and the content after 12 months of storage were detected. All samples involved in the trial were tested by the same analyst. Each parallel sample was detected by two analysts at the same time, and the arithmetic mean of both parties was taken as the final result. The test showed that the loss rate of the active ingredient silymarin in the samples during the 12-month storage period was 2.19%, 2.03% and 2.16%, respectively, with an average of 2.13%. The loss rate of the active ingredient content was not large, indicating that the product had good stability.

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PUM

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Abstract

The present invention discloses a feed additive with liver-protection functions and a preparation method thereof. The feed additive with the liver-protection functions prepared from a natural plant extract of silymarin as a main active ingredient is developed. The present invention aims to solve the technical problems that the silymarin is not stable in chemical properties, not resistant in storage and high in addition costs and how to improve application effects in animal feeds. The compound technology prepares the silymarin into a powdery coated micro-particle compound with a good fluidity,enables the silymarin content in the micro-particle compound to be kept stable for a long time and the product to be good in fluidity, effectively improves use effects, and is low in costs. Animal experiment results show that the feed additive with the liver-protection functions has very good animal liver-protecting effects and at the same time can improve growth performance of the bred animals.

Description

technical field [0001] The invention belongs to the field of animal health care, in particular to a feed additive with liver protection function and a preparation method thereof. technical background [0002] Since the reform and development, with the growth of market demand and the development of feed industry, the breeding industry has developed rapidly. At present, the total output of my country's industrial feed exceeds 200 million tons per year, and aquatic feed exceeds 18 million tons per year, ranking first in the world and occupying an important position in the world. [0003] The liver participates in the detoxification, immunity, digestion, hematopoiesis and many other functions of the animal body, and is one of the most important organs in animals. Affected by various factors such as the breeding environment, breeding density, feed quality, and breeding management, there have been many liver problems in farmed animals in recent years. Taking the aquaculture indu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/30A23K20/158A23K20/105A23K10/37A23K20/163A23K20/28A23K20/10A23K40/10A23K50/80
CPCA23K10/30A23K10/37A23K20/10A23K20/105A23K20/158A23K20/163A23K20/28A23K40/10A23K50/80Y02P60/87Y02A40/818
Inventor 曾胡龙周应芳林劲冬丁宏标陶正国
Owner GUANGZHOU LEADER BIO TECH
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