Traditional Chinese medicine composition for decreasing blood fat and preparation method

A technology for medicines and raw materials, applied in the field of blood lipid-lowering traditional Chinese medicine compositions and preparations, can solve problems such as being unfavorable to industrial production, polluting the environment with waste liquid, affecting production efficiency, etc., and achieves improvement of blood rheology and reduction of whole blood viscosity. , the effect of improving production efficiency

Active Publication Date: 2018-06-15
XIUZHENG PHARMA GRP CHANGCHUN HIGH NEW PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In the current preparation process, after the hawthorn is decocted in water, it contains more sugar, and it is not easy to filter and dry after concentration, which leads to repeated moisture absorption and affects production efficiency.
Moreover, a large amount of organic solvents are used in the extraction process, and a large amount of waste liquid pollutes the environment, which is not conducive to industrial production

Method used

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  • Traditional Chinese medicine composition for decreasing blood fat and preparation method
  • Traditional Chinese medicine composition for decreasing blood fat and preparation method
  • Traditional Chinese medicine composition for decreasing blood fat and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Recipe: Hawthorn 55kg made Polygonum multiflorum 2.5kg Cassia seed 1kg Lotus leaf 5kg

[0045] (1) Pass through No. 1 (10 mesh) to No. 4 (65 mesh) sieves after taking the medicinal material of formula quantity and pulverizing;

[0046] (2) Take the above-mentioned medicinal material powder and mix, add 10 times the amount of water and stir and mix for 60 minutes to fully moisten;

[0047] (3) The first extraction: put it in a low-temperature and high-pressure differential extractor, and extract 2 times at 5°C, the first time is 30Mpa, extraction is 60min, the second time is 40Mpa, extraction is 45min;

[0048] (4) Solid-liquid separation: the extracted slurry is centrifuged (rotating speed is 8000rpm, and the centrifugation time is 20min) or filtered to separate solid-liquid, and the solid content transferred to the extract is controlled to be no more than 20% of the total amount of medicinal materials , the separated extract is measured for later use.

[0049] (5) The ...

Embodiment 2

[0057] Recipe: Hawthorn 50kg, Polygonum multiflorum 3.5kg, Cassia seed 3.5kg, Lotus leaf 10kg.

[0058] (1) Pass through No. 1 (10 mesh) to No. 4 (65 mesh) sieves after taking the medicinal material of formula quantity and pulverizing;

[0059] (2) Take the above-mentioned medicinal material powder and mix, add 20 times the amount of water and stir and mix for 70 minutes to make it fully wet;

[0060] (3) The first extraction: put it in a low-temperature and high-pressure differential extractor, and extract 2 times at 10°C, the first time is 20Mpa, extraction is 40min, the second time is 50Mpa, extraction is 30min;

[0061] (4) Solid-liquid separation: the extracted slurry is centrifuged (rotating speed is 10000rpm, and the time of centrifugation is 15min) or filtered to separate solid-liquid, and the solid content transferred to the extract is controlled to be no more than 20% of the total medicinal material , the separated extract is measured for later use.

[0062] (5) Th...

Embodiment 3

[0071] Formula: hawthorn 60kg, Polygonum multiflorum 1kg, cassia seed 2.5kg, lotus leaf 8kg.

[0072] (1) Pass through No. 1 (10 mesh) to No. 4 (65 mesh) sieves after taking the medicinal material of formula quantity and pulverizing;

[0073] (2) Mix the medicinal material powder with the above weight, add 15 times the amount of water and stir and mix for 50 minutes to make it fully wet;

[0074] (3) The first extraction: put it in a low-temperature and high-pressure differential extractor, and extract 2 times at 0°C, the first time is 25Mpa, extraction is 30min, the second time is 45Mpa, extraction is 60min;

[0075] (4) Solid-liquid separation: the extracted slurry is centrifuged (rotating speed is 12000rpm, and the centrifugation time is 10min) or filtered to separate solid-liquid, and the solid content transferred to the extract is controlled to be no more than 20% of the total amount of medicinal materials , the separated extract is measured for later use.

[0076] (5) ...

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Abstract

The invention relates to the field of medicines, and particularly relates to a medicine and an extracting technology thereof. The extracting technology is characterized in that water is selected as asolvent, so that organic solvents can be greatly saved, and the environmental protection as well as the safety can be ensured; in addition, the low-temperature and high-pressure-difference extractingway is carried out, so that effective components can be extracted to the maximum, and as a result, the production efficiency is improved. The pharmacological research result shows that a traditional Chinese medicine composition prepared according to the extracting technology is capable of obviously reducing high cholesterol, caused by egg nog, of a mice, obviously improving hemorheology of a tested rat with hyperlipemia, decreasing whole blood viscosity, decreasing cholesterol, triglyceride and low density lipoprotein content in blood serum, and obviously decreasing the blood fat; the fat decreasing effect is obviously greater than that of Jiangzhining particles under the same dosage.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition for lowering blood fat and a preparation method thereof. Background technique [0002] Due to the improvement of the quality of life, high blood sugar, high blood fat, and high blood pressure have gradually become the three major killers that threaten human health, and they are showing a trend of rejuvenation, which has seriously affected people's quality of life. Most patients with hyperlipidemia also have symptoms of high blood pressure, which can easily lead to stroke and cardiovascular disease. If they cannot be prevented and treated early, the consequences will be very serious. [0003] Hyperlipidemia can be divided into two types: primary and secondary. Primary hyperlipidemia is related to congenital and heredity. It is caused by abnormality of apolipoprotein involved in lipoprotein transport and metabolism due to single gene defect or po...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61P3/06
CPCA61K36/482A61K36/62A61K36/704A61K36/734A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 徐建白冰徐云许艳茹张显涛李志宝徐艳霞何帆陈德峰
Owner XIUZHENG PHARMA GRP CHANGCHUN HIGH NEW PHARMA CO LTD
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