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Traditional Chinese medicine preparation with liver protection function and preparation method thereof

A technology of traditional Chinese medicine preparation and liver function, which is applied in the field of traditional Chinese medicine preparation with liver protection function and its preparation, which can solve the problems of high price, unsuitability for industrial production, and poor effect, so as to relieve dizziness, tinnitus, liver protection Good, better results

Inactive Publication Date: 2018-05-29
CHENGUANG BIOTECH GRP HANDAN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are various liver-protecting drugs or traditional Chinese medicine compositions on the market, which mainly have disadvantages such as poor effect, complicated preparation process, unsuitable for industrial production, high price, and increased life pressure of patients. Drugs for the treatment of liver diseases that are easy to prepare, have significant curative effect, and low cost have always been the wish of scientific researchers

Method used

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  • Traditional Chinese medicine preparation with liver protection function and preparation method thereof
  • Traditional Chinese medicine preparation with liver protection function and preparation method thereof
  • Traditional Chinese medicine preparation with liver protection function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Preparation method of granules

[0032] 1. Prescription

[0033] 1 part of Bupleurum, 1 part of Forsythia, 1 part of Salvia, 1 part of Turmeric, 1 part of Anemarrhena, 1 part of Pseudostellaria, and 1 part of Pinellia.

[0034] 2. Preparation method

[0035] (1) Pretreatment: Grind the 7 raw materials to pass through a 10-mesh sieve, weigh the samples according to the weight ratio, and mix them evenly;

[0036] (2) Alcohol extraction: Add 4 times the volume of 60% pure ethanol to the mixed raw materials in step (1), heat to 60°C, reflux for 0.5 hours, filter to obtain the extract, and take samples to detect the concentration of each active ingredient. Transfer rate, ethanol is recovered under reduced pressure to obtain a thick paste; the transfer rate of the extract is shown in Table 1:

[0037] Table 1 The transfer rate of the active ingredient in the ethanol extract in Example 1

[0038]

[0039] (3) Water extraction: add 4 times the volume of pure water to the...

Embodiment 2

[0043] Tablet preparation method

[0044] 1. Prescription

[0045] 5 parts of Bupleurum, 5 parts of Forsythia, 5 parts of Salvia, 5 parts of Turmeric, 5 parts of Anemarrhena, 4 parts of Pseudostellaria, and 4 parts of Pinellia.

[0046] 2. Preparation method

[0047](1) Pretreatment: Grind the 7 raw materials to pass through a 100-mesh sieve, weigh the samples according to the weight ratio, and mix them evenly;

[0048] (2) Alcohol extraction: Add 14 times the volume of 95% pure ethanol to the mixed raw materials in step (1), heat to 90°C, reflux for 3 hours, filter to obtain the extract, and take samples to detect the concentration of each active ingredient. Transfer rate, ethanol is recovered under reduced pressure to obtain a thick paste; the transfer rate of the extract is shown in Table 2:

[0049] The transfer rate of active ingredient in the ethanol extract in table 2 embodiment 2

[0050]

[0051] (3) Water extraction: add 14 times the volume of pure water to th...

Embodiment 3

[0055] The preparation method of capsule

[0056] 1. Prescription

[0057] 3 parts of Bupleurum, 3 parts of Forsythia, 3 parts of Salvia, 3 parts of Turmeric, 3 parts of Anemarrhena, 2 parts of Pseudostellaria, and 1 part of Pinellia.

[0058] 2. Preparation method

[0059] (1) Pretreatment: Grind the 7 raw materials to pass through a 50-mesh sieve, weigh the samples according to the weight ratio, and mix them evenly;

[0060] (2) Alcohol extraction: Add 8 times the volume of 75% pure ethanol to the mixed raw materials in step (1), heat to 85°C, reflux for 1.5 hours, filter to obtain the extract, and take samples to detect the concentration of each active ingredient. Transfer rate, ethanol is recovered under reduced pressure to obtain a thick paste; the transfer rate of the extract is shown in Table 3:

[0061] The transfer rate of active ingredient in the ethanol extract in table 3 embodiment 3

[0062]

[0063] (3) Water extraction: add 6 times the volume of pure wate...

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Abstract

The invention discloses a traditional Chinese medicine preparation with a liver protection function and a preparation method thereof. The traditional Chinese medicine preparation comprises the following medicinal compositions: radix bupleuri, phillyrin, salviae miltiorrhizae, rhizoma curcumae longae, rhizoma anemarrhenae, rhizoma anemarrhenae and rhizoma pinellinae praeparata. The traditional Chinese medicine preparation is prepared by the following steps: respectively smashing raw materials, weighing samples according to a weight ratio, uniformly mixing the samples, and performing ethanol extraction, water extraction, spray drying, preparation of the traditional Chinese medicine preparation and the like, so as to obtain the preparation. The traditional Chinese medicine preparation is usedfor improving the liver function and has an effect of treating chemical liver injury. The traditional Chinese medicine preparation is refined by taking the modern traditional Chinese medicine theoryas a basis, adopting traditional Chinese medicines as the raw materials, applying the modern scientific method for extraction and adopting an advanced production process and a modern detection means;the traditional Chinese medicine preparation is simple and easily available in raw materials, simple and convenient in extraction methods, stable in product quality and lower in cost, so that the traditional Chinese medicine preparation is suitable for industrial production and has better social benefits and economic benefits.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a traditional Chinese medicine preparation with liver protection function and a preparation method thereof. Background technique [0002] my country is one of the countries with a high incidence of liver disease. Due to excessive living pressure and deteriorating living or working environment, the number of liver injuries caused by exposure to chemical poisons (such as alcohol or other toxic substances) is also increasing, especially Alcoholism and alcoholism are increasing day by day, or the number of workers engaged in chemical drug synthesis, chemical production and other industries with chemical liver injury is gradually increasing, and the number of patients with acute and chronic hepatitis caused by chemical liver injury is also gradually increasing. The most prominent symptoms of liver disease are fatigue and lack of appetite. Common symptoms include distendin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16
CPCA61K36/233A61K36/36A61K36/537A61K36/634A61K36/8888A61K36/8964A61K36/9066A61K2236/331A61K2236/333A61K2236/51A61K2300/00
Inventor 薛强周海平李卫民黄燕巧连运河
Owner CHENGUANG BIOTECH GRP HANDAN CO LTD
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