Agarwood extract with hypoglycemic effect and application thereof

An agarwood extract and blood sugar-lowering technology, which is applied in the field of agarwood, can solve the problem of slow blood sugar lowering in traditional Chinese medicine, shorten the treatment cycle, and improve the effect of treatment

Active Publication Date: 2021-03-30
海南现代农林发展控股集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing western medicines for hypoglycemia can quickly lower blood sugar, but only temporarily, and long-term use can damage the liver and kidneys.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A kind of agarwood extract with hypoglycemic effect, said agarwood extract is prepared by the method comprising the following steps:

[0023] S1. Soaking: cut wild agarwood or artificial agarwood into pieces, and soak in saline with a mass concentration of 5% for 50 minutes at a temperature of 70°C;

[0024] S2. Steam explosion: Put the soaked agarwood into a steam explosion tank for steam explosion. The pressure of the steam explosion is 3MPa, the temperature is 100°C, and the maintenance pressure is 5min;

[0025] S3, enzymatic hydrolysis: use amylase and cellulase to treat for 2 hours after steam explosion, use 10g amylase and 5g cellulase per kilogram of agarwood;

[0026] S4. Extraction: after enzymolysis, wash, dry, crush to 80 mesh, use organic solvent ethyl acetate for reflux extraction, extract at 70°C for 3 hours, repeat the extraction twice, combine the extracts, concentrate and dry to obtain the extract;

[0027] S5, secondary extraction: put the extract in...

Embodiment 2

[0029] A kind of agarwood extract with hypoglycemic effect, said agarwood extract is prepared by the method comprising the following steps:

[0030] S1. Soaking: cut wild agarwood or artificial agarwood into pieces, and soak in saline with a mass concentration of 10% for 30 minutes at a temperature of 100°C;

[0031] S2. Steam explosion: put the soaked agarwood into a steam explosion tank for steam explosion. The pressure of steam explosion is 5MPa, the temperature is 120°C, and the maintenance pressure is 3min;

[0032] S3, enzymatic hydrolysis: use amylase and cellulase to treat for 1 hour after steam explosion, use 20g amylase and 15g cellulase per kilogram of agarwood;

[0033] S4. Extraction: After enzymatic hydrolysis, wash, dry, crush to 100 mesh, use organic solvent chloroform or diethyl ether for reflux extraction, extract at 80°C for 1 hour, repeat the extraction 4 times, combine the extracts, concentrate and dry to obtain the extract;

[0034] S5, secondary extract...

Embodiment 3

[0036] A kind of agarwood extract with hypoglycemic effect, said agarwood extract is prepared by the method comprising the following steps:

[0037] S1. Soaking: cut wild agarwood or artificial agarwood into pieces, and soak in saline with a mass concentration of 8% for 40 minutes, and the soaking temperature is 85°C;

[0038] S2. Steam explosion: put the soaked agarwood into a steam explosion tank for steam explosion. The pressure of steam explosion is 4MPa, the temperature is 110°C, and the maintenance pressure is 4min;

[0039] S3, enzymatic hydrolysis: use amylase and cellulase to treat for 1.5 hours after steam explosion, use 15g amylase and 10g cellulase per kilogram of agarwood;

[0040] S4. Extraction: After enzymatic hydrolysis, wash, dry, crush to 90 mesh, use organic solvent ethanol for reflux extraction, extract at 75°C for 2 hours, repeat the extraction 3 times, combine the extracts, concentrate and dry to obtain the extract;

[0041] S5, secondary extraction: pu...

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PUM

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Abstract

The invention discloses a lignum aquilariae resinatum extract with a blood sugar lowering function and application thereof. The lignum aquilariae resinatum extract is prepared through a method comprising the following steps of dicing lignum aquilariae resinatum, and putting into a saline solution and soaking; carrying out steam explosion on the soaked lignum aquilariae resinatum; afterwards, treating by utilizing amylase and cellulase; afterwards, cleaning, oven-drying, crushing, carrying out reflux extraction by adopting an organic solvent, repeatedly extracting for 2 to 4 times, merging extracting solutions, concentrating and drying to obtain a concrete; carrying out CO2 supercritical extraction on the concrete, so as to obtain the lignum aquilariae resinatum extract with the blood sugarlowering function. All the steps of the extract provided by the invention mutually have synergistic effects; a blood sugar lowering effective component in the lignum aquilariae resinatum is sufficiently extracted, and the lignum aquilariae resinatum extract with the blood sugar lowering function, which is used for efficiently lowering blood sugar, is obtained.

Description

technical field [0001] The invention relates to the technical field of agarwood, in particular to an agarwood extract with hypoglycemic effect and application thereof. Background technique [0002] Agarwood is the xylem of Agarwood or white wood that contains black resin. The former is mainly produced in India, Malaysia and other places, and our country calls it imported agarwood, while the latter is mainly produced in Hainan, Guangdong, Guangxi and other provinces and regions in my country, and is called domestic agarwood or soil agarwood. Agarwood is not only a traditional precious medicinal material in my country, Japan, India and other Southeast Asian countries, but also a precious natural spice. Agarwood has a history of at least 3,000 years in the Middle East, China, and Japan. It is also recorded in India and France, and even in the Old Testament of the Bible. At present, agarwood is still one of the most expensive spices in the world, and the value of agarwood expo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/835A61P3/10A23L33/105
CPCA23V2002/00A61K36/835A61K2236/19A61K2236/31A61K2236/331A61K2236/35A61K2236/37A23L33/105A23V2250/21A23V2200/328
Inventor 戴好富梅文莉董文化李薇
Owner 海南现代农林发展控股集团有限公司
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