Traditional Chinese medicine pill for primary biliary cirrhosis and preparation method thereof

A technology of biliary liver cirrhosis and traditional Chinese medicine pills, which is applied in pill delivery, pharmaceutical formulas, medical preparations containing active ingredients, etc. It can solve the problems of poor patient compliance, high clinical costs, and obvious side effects of patients, and achieve good curative effect Effect

Inactive Publication Date: 2018-05-18
张岚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, ursodeoxycholic acid (UDCA) is the only Western medicine that has been proven effective in the treatment of this disease by controlled clinical trials. However, studies have shown that UDCA cannot reduce the mortality rate and liver transplantation rate, and due to long-term application, some patients have obvious side effects. High clinical costs and poor patient compliance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0065] 20-40 parts of astragalus, 20-40 parts of milk ginseng, 20-35 parts of corn silk, 20-35 parts of Xihuangcao,

[0066] 15-30 parts of cornus, 15-30 parts of sedge, 15-30 parts of sedge, 15-30 parts of wolfberry leaves,

[0067] 15-25 parts of Akebia root, 15-25 parts of Datian Jihuang, 10-20 parts of licorice, 10-20 parts of black sesame,

[0068] 10-20 parts of birch bark, 10-20 parts of Phnom Penh rabbit ears, 9-15 parts of salvia miltiorrhiza, 9-15 parts of coriander,

[0069] 9-15 parts of Limegrass, 6-12 parts of variegated orchid, 6-12 parts of Chuanxiong, 4-10 parts of Kingsberry,

[0070] 4-10 parts of Nantian bamboo stalks, 3-9 parts of horned ginseng, 3-9 parts of yellow grass flowers, and 1-5 parts of watermelon seeds.

[0071] The processing steps of the pharmaceutical preparation method of the present invention are:

[0072] (1) Milk ginsen...

Embodiment 2

[0081] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0082] 25-35 parts of astragalus, 25-35 parts of milk ginseng, 24-30 parts of corn silk, 24-30 parts of Xihuangcao,

[0083] 18-25 parts of cornus, 18-25 parts of sedge, 18-25 parts of sedge, 18-25 parts of wolfberry leaves,

[0084] 18-22 parts of Akebia root, 18-22 parts of Datian Jihuang, 12-18 parts of licorice, 12-18 parts of black sesame,

[0085] 12-18 parts of birch bark, 12-16 parts of Phnom Penh rabbit ears, 10-13 parts of salvia miltiorrhiza, 9-12 parts of coriander,

[0086] 9-12 parts of Limegrass, 7-10 parts of variegated orchid, 7-10 parts of Chuanxiong, 5-8 parts of Kingsberry,

[0087] 5-8 parts of Nantian bamboo stalks, 4-7 parts of horned ginseng, 4-7 parts of yellow grass flowers, and 2-4 parts of wave-edge melon seeds.

[0088] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those i...

Embodiment 3

[0090] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0091] 32 parts of astragalus, 30 parts of milk ginseng, 28 parts of corn silk, 26 parts of Xihuangcao,

[0092] 22 parts of Cornus, 22 parts of Diaobangui, 22 parts of Cyperus, 22 parts of Chinese wolfberry leaves,

[0093] 20 parts of Akebia root, 20 parts of Datian base yellow, 16 parts of licorice, 16 parts of black sesame,

[0094] 15 parts of birch bark, 15 parts of Phnom Penh rabbit ears, 12 parts of salvia miltiorrhiza, 10 parts of coriander,

[0095] 10 parts of Limegrass, 8 parts of Variegated Orchid, 8 parts of Chuanxiong, 7 parts of Kingsberry,

[0096] 7 parts of Nantian bamboo stalks, 6 parts of ginseng, 6 parts of yellow grass flowers, and 3 parts of wave-lens melon seeds.

[0097] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

[0098] clinical information:

[0099...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine pill for primary biliary cirrhosis and a preparation method thereof and belongs to the field of traditional Chinese medicines. Raw materials of an active pharmaceutical ingredient of the traditional Chinese medicine pill consist of astragalus membranaceus, phoenix hawksbeard roots, stigmata maydis, serrate rabdosia herbs, fructus corni, perfoliate knotweed herbs, nutgrass flatsedge, Chinese holly leaves, fiveleaf akebia roots, lysimachia fortunei maxim, liquorice, black sesame, Japanese white birch barks, frangrant ainsliaea herbs, radix salviae miltiorrhizae, lawn pennywort herbs, scarlet swertia herbs, goodyera schlechtendaliana, ligusticum wallichii, hypericum patulum, common nandina branchlet, whorledleaf solomonseal rhizome, corydalis adunca maxim and semen herpetospermi. The traditional Chinese medicine pill disclosed by the invention selects the medicinal materials conforming to a principle of the emperor and the minister, is applied aiming at pathogenesis, have the efficacies of reinforcing liver and kidney, tonifying spleen, assisting transportation, clearing away liver fire, benefiting gallbladder, promoting Qi to activate blood, removing blood stasis, dredging collateral, promoting the circulation of Qi, expelling stagnation, clearing away heat, promoting diuresis and removing toxicity for detumescence, is good in absorption effect, significant in treatment effect, free from toxic and side effects and clinical adverse reaction and has higher cure rate for the primary biliary cirrhosis through clinical verification.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine pill for primary biliary cirrhosis and a preparation method thereof. Background technique [0002] Primary biliary cirrhosis (primary biliary cirrhosis, PBC) is a chronic progressive cholestatic liver disease of unknown cause. Inflammation in the portal area and debris in the liver parenchyma eventually progressed to cirrhosis. Primary biliary cirrhosis is a chronic disease. Most of the patients are women. The age of onset is generally 35 to 65 years old. It may be related to autoimmunity. Clinically, it is characterized by skin itching, jaundice, and hepatosplenomegaly. At present, ursodeoxycholic acid (UDCA) is the only Western medicine that has been proven effective in the treatment of this disease by controlled clinical trials. However, studies have shown that UDCA cannot reduce the mortality rate and liver transplantation rate, and...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K9/20A61P1/16
CPCA61K9/2068A61K36/185A61K36/23A61K36/236A61K36/28A61K36/29A61K36/38A61K36/40A61K36/42A61K36/481A61K36/484A61K36/51A61K36/53A61K36/537A61K36/66A61K36/704A61K36/8905A61K36/8969A61K36/898A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 张岚姜昊君
Owner 张岚
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