Skin nursing product customization method for improving allergic skin

A technology for skin care products and allergies, applied in the field of skin care products, can solve problems such as skin discomfort, waste of time and financial resources, achieve good skin care effects, accurate test results, and solve skin sensitivity effects

Pending Publication Date: 2018-05-08
杜立波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current method commonly used by consumers is to use the method of selection-purchase-try to verify whether the skin care products that improve allergic skin quality are suitable for them. In this process, consumers not only waste a lot of time and financial resources, but also may cause skin damage. unwell

Method used

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  • Skin nursing product customization method for improving allergic skin
  • Skin nursing product customization method for improving allergic skin
  • Skin nursing product customization method for improving allergic skin

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0114] The preparation method of the skin care product for improving allergic skin quality generally comprises the following steps:

[0115] Step 5a) According to the sensitivity of the user, select moisturizers, oils, organic solvents, preservatives, solubilizers, thickeners, skin conditioning agents, chelating agents, antioxidants, polypeptides, Fragrance, desensitizer and water;

[0116] Step 5b) mixing the solubilizing agent, antioxidant, grease, organic solvent and fragrance in an emulsifier at a high speed to prepare a mixture A;

[0117] Step 5c) Put the first group of humectants into the stirring pot and stir to dissolve to prepare the mixture B;

[0118] Step 5d) Add the second group of humectants, chelating agents, and thickeners into the stirring pot, heat up to 85-95°C while stirring, fully dissolve them, and keep them warm for 15-20 minutes to prepare mixture C;

[0119] Step 5e) Cool mixture C to 40-45°C, add skin conditioner, anti-sensitivity agent and polypep...

Embodiment 1

[0122] In Example 1 of the present invention, gene detection was carried out on a 55-year-old volunteer 1, and the detected genes included: allergy-related genes FLG, DDB2, and NLRP3. According to the test results, a skin care product with the following formula is prepared for it: wherein, the total mass of the skin care product is 50Kg in total,

[0123]

[0124]

[0125] Volunteer 1 used the skin care product for improving allergic skin quality of the above formula for 100 days and then performed genetic testing again. The relative gene expression before and after using the skin care product for improving allergic skin quality is shown in Table 5:

[0126] table 5

[0127] gene name

FLG

DDB2

NLRP3

GAPDH

before use

3.514534

1.60956

3.482202

1

After use

5.62326

1.223476

2.12687

1

Reference example

2.971445

1.65306

2.976469

1

[0128] Wherein, the reference example of Examples 1-4 is t...

Embodiment 2

[0131] Example 2 of the present invention conducts gene detection on volunteer 2 aged 45, and the detected genes include: allergy-related genes FLG, DDB2, and NLRP3. According to the test results, a skin care product with the following formula is prepared for it: wherein, the total mass of the skin care product is 50Kg in total,

[0132] The first group of moisturizers: polyglutamic acid 1Kg, Tremella polysaccharide 1Kg, Ganoderma lucidum polysaccharide 1Kg

[0133] The second group of moisturizers: butanediol 0.2Kg, dipropylene glycol 0.8Kg, glycerin 5Kg

[0134] Fat: almond oil 1Kg, squalane 0.5Kg, argan oil 0.5Kg, jojoba oil 1.5Kg

[0135] Organic solvent: docosanol 1Kg, cetyl alcohol 1.2Kg

[0136] Preservative: iodopropynyl butyl carbamate 0.12Kg

[0137] Solubilizer: PEG20 hydrogenated castor oil 0.8Kg, PEG20 glyceryl stearate 1.1Kg, PEG60 hydrogenated castor oil 0.8Kg

[0138] Thickener: hydroxymethyl cellulose 1Kg

[0139] Skin conditioner: ginseng root extract 1....

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Abstract

The invention discloses a skin nursing product customization method for improving allergic skin. The method includes the following steps of collecting cell samples of users; extracting mRNAs of the cell samples; conducting inverse transcription on the mRNAs to synthesize cDNAs; detecting the polymorphism of correlative allergy genes in the cDNAs and the corresponding expression quantity of the cDNAs, wherein the correlative allergy genes comprise at least one of FLG, DDB2 and NLRP3; according to the polymorphism of the genes and the corresponding expression quantity of the cDNAs, judging the sensitivity, selecting skin nursing components and dosage for improving the allergic skin according to the sensitivity, and preparing appropriate skin nursing products for improving the allergic skin.According to the method, by measuring the expression quantity of the correlative allergy genes, the sensitivity of different users is obtained, and the appropriate skin nursing products for improvingthe allergic skin are prepared according to the specific sensitivity of the users.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to a method for customizing skin care products for improving allergic skin quality. Background technique [0002] With the development of science and technology, the whole human gene spectrum can already be obtained by sequencing. A large number of current studies have shown that the state of human skin is closely related to genes. The genotype (or gene single nucleotide polymorphism, SNPs, referred to as polymorphism) of specific sites in these allergy-related genes can greatly affect the state of the skin, and different genotypes are the cause of skin problems. key factor. People can discover or predict skin problems by detecting different genotypes, and use this as a guide to choose appropriate skin care products for improving allergic skin quality. Further research found that, in addition to genotype, the expression protein caused by genotype is the key factor lead...

Claims

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Application Information

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IPC IPC(8): C12Q1/6888A61K8/9789A61K8/49A61K8/63A61K8/64A61Q19/00A61P37/08
CPCA61K8/4926A61K8/63A61K8/64A61K8/645A61K8/97A61Q19/005C12Q1/6888C12Q2600/156C12Q2600/158
Inventor 杜立波
Owner 杜立波
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