Preparation method of dendrobium officinale lozenge tablet

Dendrobium candidum and its production method are applied in the direction of medical preparations containing active ingredients, medical preparations with non-active ingredients, and pharmaceutical formulas, which can solve problems such as increasing production costs, increasing equipment investment, and affecting drug efficacy. Effects of avoiding hazards and reducing production costs

Inactive Publication Date: 2018-05-08
龙里县泽洋生态科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The tablet adopts 100% Dendrobium officinale composition, and adopts Dendrobium officinale itself to punch pulp as an adhesive during preparation so that there is no need to add auxiliary materials such as adhesive, so that the product is more beneficial to health; however, the buccal tablet requires Add a large amount of 50~95% alcohol (as wetting agent, the ratio of alcohol and Dendrobium officinale superfine powder is (0.2~1) mL / g), this has following deficiency: on the one hand, the adding of a large amount of alcohol has greatly improved the production of product cost; on the other hand, even if you choose to recycle alcohol, it will increase the investment in equipment, which will lead to a further increase in product production costs; on the other hand, a large amount of alcohol may also affect the tablets due to residual alcohol. drug effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1) Cleaning: put the fresh strips of Dendrobium officinale in an ultrasonic cleaner, ultrasonically treat them at 25-40kHz for 10-15min, and then take them out to dry;

[0018] 2) Drying: clean and dry, then place in a dryer and dry at 60-70°C (control the moisture content to 8%) to obtain dried Dendrobium officinale;

[0019] 2) Pulverization: the obtained dried Dendrobium candidum is placed in an ultrafine pulverizer to be pulverized, and passed through a 400-mesh sieve to obtain a superfine powder of Dendrobium candidum;

[0020] 3) Pulping: take fresh Dendrobium candidum branches and place them in a fruit beater, add water to make a pulp according to the ratio of 100g: 1000mL of fresh Dendrobium candidium branches and distilled water, pass through a 200-mesh sieve, and then use a high-pressure homogenizer to homogenize. Mass pressure is 40MPa, make viscous fresh juice, carry out short-term sterilization (temperature is 90~95 ℃, time is 60s) afterwards, cool to room ...

Embodiment 2

[0027] Repeat Example 1, the difference is:

[0028] The ratio of fresh dendrobium candidum branch and distilled water in step 3) is: 25g: 1000mL;

[0029] In step 4), the ratio of the superfine powder of Dendrobium candidum and the juice of Dendrobium candidum is: 3500g: 1000ml.

Embodiment 3

[0031] Repeat Example 1, the difference is:

[0032] The ratio of fresh dendrobium candidum branch and distilled water in step 3) is: 50g: 1000mL;

[0033] In step 4), the ratio of the superfine powder of Dendrobium candidum and the juice of Dendrobium candidum is: 3000g: 1000ml.

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Abstract

The invention discloses a dendrobium officinale lozenge tablet and its preparation method. The preparation method comprises 1) pretreating fresh strips of dendrobium officinale, 2) taking the dried dendrobium officinale and carrying out superfine grinding, 3) placing the dendrobium officinale ultrafine powder in an ice grinding machine and mixing the dendrobium officinale ultrafine powder and water to obtain a dendrobium officinale raw liquid, 4) weighing the dendrobium officinale ultrafine powder and dendrobium officinale juice and carrying out uniform mixing to obtain a soft dendrobium officinale material, and 5) carrying out granulation, drying, tabletting and sterilization on the soft dendrobium officinale material through conventional processes. The dendrobium officinale lozenge tablet contains a dendrobium officinale ingredient, is free of auxiliary materials and is pure. The juice obtained through adding water into fresh dendrobium officinale and grinding the dendrobium officinale is used as a binder and a wetting agent for dendrobium officinale lozenge tablet preparation. The preparation method is free of accessories such as other binders and wetting agents, effectively guarantees the product health, is free of additives and alcohol as a wetting agent, greatly reduces a production cost and prevents additive eating damage.

Description

technical field [0001] The invention relates to a dendrobium officinale buccal tablet and a preparation method thereof, belonging to the technical field of preparation of traditional Chinese medicine or health care products. Background technique [0002] Dendrobium officinale (scientific name: Dendrobium officinale Kimuraet Migo): erect stem, cylindrical, 9-35 cm long, 2-4 mm thick, unbranched, multi-noded; two rows of leaves, papery, oblong-lanceolate, Margins and ribs are often lavender. Racemes often emanate from the upper part of old stems that have fallen leaves, with 2-3 flowers; bracts dry membranous, light white, ovate, 5-7 mm long, sepals and petals yellow-green, nearly similar, oblong lanceolate, lip white, with a green or yellow callus at the base, ovate-lanceolate, slightly shorter than sepals, reflexed in the middle. Stamens yellow-green, about 3mm long, with 1 purple spot on both sides of apex; medicine cap white, long ovate-triangular, about 2.3mm long, apex...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K9/20A61K47/46A61P1/14
CPCA61K36/8984A61K9/0056A61K9/2068A61K2236/15A61K2236/31
Inventor 谢泽洋
Owner 龙里县泽洋生态科技有限公司
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