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Traditional Chinese medicinal composition having auxiliary protecting effect on chemical liver injury and preparation of traditional Chinese medicinal composition

A technology of chemical liver injury and protective effect, applied in the direction of drug combination, medical preparations containing active ingredients, application, etc., can solve the problems of toxic side effects, unsatisfactory curative effect, etc., and achieve the effect of definite curative effect

Inactive Publication Date: 2018-03-09
吉林省密之康药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the prevention and treatment of chemical liver injury, although membrane protective agents, anti-lipid peroxidants and immunomodulators have been developed to protect the liver, the curative effect is not satisfactory, and there are toxic and side effects, while some have the functions of promoting blood circulation, removing blood stasis, clearing liver and so on. Detoxification, liver-enhancing and liver-enhancing Chinese herbal medicines or health foods developed from their extracts have been widely recognized and have broad prospects for development and utilization

Method used

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  • Traditional Chinese medicinal composition having auxiliary protecting effect on chemical liver injury and preparation of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition having auxiliary protecting effect on chemical liver injury and preparation of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition having auxiliary protecting effect on chemical liver injury and preparation of traditional Chinese medicinal composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Schisandra medicinal material, dried at low temperature, crushed, passed through a 16-mesh sieve, weighed a certain amount, added 90% ethanol for reflux extraction once, and then extracted with water twice, 2h / time, with 4 times the amount of solvent, filtered, The filtrates were combined, concentrated, and dried by microwave to obtain the extract of Schisandra chinensis. The total flavonoid content was determined to be 58.47 mg / g by the sodium nitrite-aluminum nitrate colorimetric method, and it was set aside.

Embodiment 2

[0022] Example 2: 160 g of schisandra extract, 100 g of versicolor polysaccharide, and 150 g of milk thistle extract. The schisandra extract, versicolor polysaccharide, and milk thistle extract are mixed according to the weight ratio to obtain formula 1.

Embodiment 3

[0023] Example 3: 120 g of Schisandra chinensis extract, 60 g of Yunzhi polysaccharide, and 110 g of milk thistle extract. The schisandra extract, versicolor polysaccharide and milk thistle extract are mixed according to the weight ratio to obtain formula 2.

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Abstract

The invention belongs to the technical field of traditional Chinese medicinal preparations and particularly relates to a traditional Chinese medicinal composition having an auxiliary protecting effecton chemical liver injury and a preparation of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition disclosed by the invention is prepared from the following components by weight: 12 to 20 parts of fructus schisandrae extract, 6 to 14 parts of coriolus versicolor polysaccharide and 11 to 19 parts of fructus silybi extract. The medicines are combined to obtain a medicinal formula for auxiliary treatment of the chemical liver injury by aiming at main causes of the chemical liver injury. The traditional Chinese medicinal composition disclosed by the invention has the following advantages: (1) greenness and nature; (2) definite curative effects; (3) no side effect.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition and a preparation thereof which have an auxiliary protective effect on chemical liver damage. Background technique: [0002] The liver is the largest and most important digestive gland in the human digestive system and has important digestive functions. The liver is also the main hematopoietic organ of the fetus and the main metabolic organ and defense organ of the human body. It implements its powerful defense and detoxification function against many harmful factors external to the human body and produced by metabolism. Generally, the liver has a strong biotransformation and detoxification function for external chemical poisons. While this kind of defense against harmful factors damages the body, the liver itself is also inevitably damaged. [0003] Clinically, chemical liver injury mainl...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/57A61K9/20A61P1/16A23L33/105A23L33/125A61K31/715
CPCA23V2002/00A61K9/2059A61K31/715A61K36/28A61K36/57A61K36/79A61K2236/331A61K2236/333A61K2236/39A61K2300/00A23V2200/32A23V2250/21A23V2250/51A23V2250/5118A23V2250/5114A23V2250/1886
Inventor 殷军韩娜曹艳关晓莹刘志惠
Owner 吉林省密之康药业有限责任公司
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