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Lansoprazole tablet composition

A lansoprazole tablet and a technology for lansoprazole are applied in the field of medicine to achieve good therapeutic effect, reduce total lipid content, and reduce hydroxyproline content.

Inactive Publication Date: 2018-02-16
滁州先奇工业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report on the combined application of lansoprazole and benzbromarone in the prior art, especially no report on the prevention or treatment of gout after the combined application of the two

Method used

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  • Lansoprazole tablet composition
  • Lansoprazole tablet composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: get lansoprazole 10g, benzbromarone 30g, starch 20g, pulverize, mix uniformly, make adhesive preparation with appropriate amount of water, add appropriate amount of lubricant talcum powder, tabletting.

Embodiment 2

[0018] Embodiment 2: get lansoprazole 10g, benzbromarone 50g, dextrin 20g, pulverize, mix uniformly, do adhesive preparation with appropriate amount of water, add appropriate amount of lubricant micropowder silica gel, tabletting.

Embodiment 3

[0019] Embodiment 3: get lansoprazole 10g, benzbromarone 40g, microcrystalline cellulose 20g, pulverize, mix uniformly, make adhesive preparation with appropriate amount of water, add appropriate amount of lubricant talcum powder, tabletting.

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PUM

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Abstract

The invention belongs to the field of medicines, and discloses a lansoprazole tablet composition, which contains the active components i.e., lansoprazole and benzbromarone with the weight ratio being1:(3 to 5). The invention discloses combined application of the lansoprazole and the benzbromarone on remarkably reducing an experimental hyperuricemia mice blood uric acid level, and the lansoprazoletablet composition has an effect on treating gout.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a lansoprazole tablet composition. Background technique [0002] Lansoprazole (lansoprazole), alias dacopron, lansonazol, is a white crystalline powder chemical. Chemical name 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]-sulfinyl]-1H-benzimidazole, molecular formula is C16H14F3N3O2S with a molecular weight of 369.36100. Levetiracetam is a new type of drug that inhibits gastric acid secretion. It is mainly used clinically to treat gastric ulcer, duodenal ulcer, reflux esophagitis, Zollinger-Ellison syndrome (gastrinoma) . [0003] Benzbromarone is a derivative of benzofuran, which can inhibit the reabsorption of uric acid by renal tubules and thus reduce the concentration of uric acid in blood. It is easily absorbed orally, and its metabolites are effective. The uric acid in the blood 24 hours after taking the medicine is 66.5% of that before taking the medicine....

Claims

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Application Information

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IPC IPC(8): A61K31/4439A61K9/20A61P1/16A61P19/06A61K31/343
CPCA61K31/4439A61K9/2054A61K9/2059A61K31/343A61K2300/00
Inventor 孙本如赵菊兰
Owner 滁州先奇工业科技有限公司
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