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Preparation method of medicine for treating chronic eczema

A technology for chronic eczema and medicine, which is applied in the field of preparation of medicine for treating chronic eczema, can solve problems such as bacterial infection, and achieve the effect of easy acceptance, stable quality and good mechanical properties

Inactive Publication Date: 2018-02-06
CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, symptomatic treatment is mostly used clinically, and there are bacterial infections that cannot be ignored in the treatment, especially the lesion site has affinity for Staphylococcus aureus

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A kind of preparation method of the medicine for treating chronic eczema of the present embodiment, comprises the following steps:

[0023] (1) Add 20g of calamine powder and 10g of paeonol into 250g of ethanol, stir to dissolve, and obtain a mixed solution for use;

[0024] (2) Sprinkle 4g ​​of polyvinyl alcohol evenly to make it swell naturally;

[0025] (3) Add 1.0 g of ciclopirox olamine, stir constantly, and add ethanol to 1000 mL;

[0026] (4) Adjust the pH to 6.0~7.0, stir well, and then it can be used as a medicine for treating chronic eczema.

[0027] The specific implementation process is to clean the affected area, apply the prepared medicine for treating chronic eczema evenly on the surface of the affected area, and after it dries naturally, a gel-like film with a thickness of 1 to 3 mm will be formed. After 3 to 5 hours, the medicine in the film After the administration is complete, tear it off from the surface of the affected area, apply new medicine, 1-...

Embodiment 2

[0029] In this embodiment, on the basis of the above embodiments, the stirring process of the step (1) is further defined, which is mainly completed by a magnetic stirrer. The magnetic stirrer utilizes the characteristic of homosexual repulsion of magnetic substances to drive the magnetic stirrer to rotate by constantly changing the polarity of the two ends of the base, and the rotation of the magnetic stirrer drives the sample to rotate, so that the medicine is evenly mixed; the magnetic stirrer adopts high-quality DC The motor has low noise and stable speed regulation; the fully enclosed heating plate can be used for auxiliary heating and can be used for long-term heating; the stirring bar made of PTFE and high-quality magnetic steel is resistant to high temperature, wear and chemical Corrosion and strong magnetism; it can be mixed in a closed container, which is ideal and convenient to use; the temperature and temperature display of the agitator can be set and used for long-...

Embodiment 3

[0031] In this embodiment, on the basis of the above embodiments, the mixing container for the mixed solution in the step (3) is further defined as a 1200ml large beaker. Other steps in this embodiment are the same as those in the above embodiment, and will not be repeated here.

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PUM

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Abstract

The invention discloses a preparation method of a medicine for treating chronic eczema, comprising the following steps: 1) adding 20 g of calamine powder and 10 g of paeonol to 250 g of ethanol, stirring and dissolving to obtain a mixed solution for use; Sprinkle 4g ​​of polyvinyl alcohol evenly to make it swell naturally; 3) Add 1.0g of ciclopirox amine, stir continuously, and add ethanol to 1000mL; 4) Adjust pH to 6.0~7.0, stir well, and then it can be used for treatment Chronic eczema medication. In the present invention, calamine powder and paeonol have obvious effects on inhibiting bacteria. Calamine powder and paeonol are prepared into medicines. Due to the transdermal technology of laurofen, the penetration force of the skin and limbs of the medicine is increased, showing The superior efficacy of film coating agent on chronic eczema; the drug for the treatment of chronic eczema made of polyvinyl alcohol, non-greasy, easy to spread, strong adhesion, has a certain tear strength, easy to use, no irritation to the skin sex.

Description

technical field [0001] The invention relates to the field of preparation of coating agents, in particular to a preparation method of medicine for treating chronic eczema. Background technique [0002] Eczema is a skin inflammatory reaction caused by complex internal and external factors. Chronic eczema is generally limited and has infiltration and hypertrophy, severe itching, and easy recurrence. The etiology of the disease is complex, and internal and external factors interact, often in many ways. Patients often have allergic constitution, which is related to genetic factors, so it occurs in specific groups of people. [0003] Chronic eczema is generally limited and has infiltration and hypertrophy, severe itching, and easy recurrence. Chronic eczema mostly develops because of acute and subacute eczema outbreaks repeatedly, and chronic inflammation can also appear at the beginning. The skin in the affected area becomes infiltrated and thickened, turning dark red and pig...

Claims

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Application Information

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IPC IPC(8): A61K33/30A61K47/22A61P17/00A61K31/12
CPCA61K33/30A61K31/12A61K47/22A61K2300/00
Inventor 张蛟
Owner CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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