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A traditional Chinese medicine composition for hangover and liver protection, its preparation method and application

A technology for relieving alcohol and protecting the liver and a composition is applied in the field of traditional Chinese medicine, which can solve the problems of pathological changes of organs and tissues, little effect, etc., and achieve the effects of reducing ethanol content, improving activity and proper compatibility.

Active Publication Date: 2018-06-15
哈尔滨一方堂中医药科技有限责任公司
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly uses diuretic and symptomatic treatment methods (such as naloxone) to relieve alcoholism. This type of drug has a certain effect on acute alcoholism, but for the pathological changes of organs and tissues caused by chronic alcoholism—especially for liver damage— — with little effect

Method used

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  • A traditional Chinese medicine composition for hangover and liver protection, its preparation method and application
  • A traditional Chinese medicine composition for hangover and liver protection, its preparation method and application
  • A traditional Chinese medicine composition for hangover and liver protection, its preparation method and application

Examples

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Effect test

preparation example Construction

[0033] The preparation examples and effect test examples of the present application are described in more detail below to facilitate the understanding of the present application.

[0034] (1) Preparation Examples

preparation example 1

[0036] Step (1): Add 2500g of kudzu flower, 2500g of Hovenia dulcis, 1000g of Divine Comedy, 2500g of white cocos, 1000g of white poria cocos, 1000g of ginseng, 1500g of raw hawthorn and 1500g of schisandra, add 8 times the amount of 108L 60% ethanol aqueous solution to reflux and extract twice , each time for 1 hour, after filtering to obtain the alcohol extract;

[0037] Step (2): Add 8 times the amount, that is, 108 L of water to the dregs after ethanol extraction, decoct twice, each time for 1 hour, and filter to obtain the water extract;

[0038]Step (3): combining the alcohol extract of step (1) with the water extract of step (2), concentrating under reduced pressure to obtain extract;

[0039] Step (4): Shell 3,000g of raw oysters, wash the soft body and mince, weigh 750g, add 4 times the amount, that is, 3L of water, extract 3 times in a constant temperature water bath shaker at 80°C, and centrifuge for 1 hour each time. , take the supernatant, combine, concentrate un...

preparation example 2

[0042] The weight of each raw material medicine is as follows: 2000g of kudzu flower, 2000g of Hovenia dulcis, 1500g of Divine Comedy, 2000g of white cocos, 1500g of white poria cocos, 1000g of ginseng, 2000g of raw hawthorn and 2000g of schisandra, and 3500g of raw oyster. According to the method of Preparation Example 1, granules were prepared.

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Abstract

This application relates to a traditional Chinese medicine composition for relieving alcoholism and protecting the liver. The power of wine dampness, regulating qi and invigorating the spleen. Pharmacological tests show that the Chinese medicinal composition of the present application can prolong the latent time of drunkenness in mice, shorten the time of drunkenness in mice, reduce the ethanol content in blood, reduce intrahepatic alanine aminotransferase (ALT), aspartic acid amino Transferase (AST) and malondialdehyde (MDA) levels can increase the activity of glutathione peroxidase (GSH‑PX) and alcohol dehydrogenase (ADH), which has excellent anti-alcoholic and liver-protecting effects.

Description

technical field [0001] The application relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for relieving alcohol and protecting the liver, its preparation method and application. Background technique [0002] China is a big wine consumption country. Moderate drinking can promote blood circulation, clear collaterals and disperse cold, which is good for your health, but excessive drinking will cause many harms to your body. In addition to acute discomfort symptoms such as dizziness, vomiting, dry mouth, and gastric bleeding, excessive drinking can also cause some organic changes, especially damage to the liver and gastrointestinal tract, such as fatty degeneration of stem cells , inflammatory necrosis and fibrosis, eventually leading to alcoholic liver disease, including alcoholic hepatitis, alcoholic fatty liver, alcoholic cirrhosis, liver failure, the most serious cases can lead to liver cancer and gast...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P39/02A61P1/16A61K35/618
Inventor 胡晓阳朴圣爱付强李响李紫薇张双良邹尚亮蒋皓
Owner 哈尔滨一方堂中医药科技有限责任公司
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