Preparation method and application of antibacterial cellulose ester

Abstract

The invention discloses a preparation method of antibacterial cellulose and application of the obtained antibacterial cellulose in preparing antibacterial fiber surgical dressing. The preparation method comprises the following steps: purifying a cellulose derivative; adding the purified cellulose derivative and acid anhydride into an acetone solution in the presence of a catalyst, heating, and stirring; activating hydroxyl in an ester, washing precipitates in absolute ethyl alcohol, performing suction filtering to obtain the ester, and obtaining a grafted ester; grafting ethylenediamine protected by di-tert-butyl dicarbonate ester and a broad-spectrum antibacterial agent; and enabling the ester to have esterification with a product, thus obtaining the antibacterial cellulose. The prepared esterification product is high in moisture absorption, a modified product of a grafted antibacterial agent has good antibacterial effect for negative and positive bacteria, the medical dressing not only can play a bacteriostatic effect when in bacterial infection, can avoid the breeding of the bacteria, also has the advantage of water resistance and water permeability, and can well protect a wound area.

Description

technical field [0001] The invention relates to the esterification modification and antibacterial performance research of cellulose diacetate, in particular to the preparation of an electrospun antibacterial fiber and its application in the field of medical dressings. Background technique [0002] Acetate fiber has a luster and feel similar to silk, and is often used as a substitute for silk, as the lining of skirts or coats, and blended with synthetic fibers to produce composite yarns for various high-end clothing. In addition to being used in textiles, acetate fiber is also widely used in medical dressings, cigarette filters and other fields. [0003] Because CA fiber has hydrophilic properties and good hygroscopic properties, it is especially suitable for anti-inflammatory and antibacterial gauze, wound dressings, etc. In a humid environment, various bacteria are easy to breed on the surface of the wound, and the gauze made of CA material can avoid excessive moisture and...

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Problems solved by technology

Cheng Chi et al. conducted an experimental analysis of the problems that often occur in the separation of serum proteins by cellulose acetate membranes, and obtained the factors that affect the electrophoretic spectrum. , resulting in different brittleness of the membrane, resulting in uneven separation effect of the entire membrane during the protein separation process, so the cellulose acetate membrane should be soaked in buffer before use, and it should not be too much during the process of filter paper drying the membrane. Dry, otherwise the sample will not be able to enter the pores of the separation membrane, and a good separation effect will not be achieved.

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