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Composition and use of Hubei crabapple and bamboo extract as active ingredients

A technology of active ingredients and compositions, applied in the field of functional foods, can solve problems such as increased burden on the liver and digestive system, limited neurotrophic effect, increased cravings, etc., to improve insulin sensitivity, inhibit central fat accumulation, prevent effects of depression

Active Publication Date: 2020-11-24
杭州阡陌棠生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Too much stress can also lead to increased cravings for some junk foods
[0012] (2) Accumulation of toxic substances: Toxins enter the body through food, water and air, and accumulation in the body will increase the burden on the liver and digestive system. Once the pressure is too high, it will cause inflammation
Products already on the market or new drugs in clinical trials are also designed to partially relieve symptoms, but do not cure the root cause
Although many laboratories at home and abroad are developing peptide mimetic agonists and monoclonal antibodies based on the binding of BDNF to the TrkB receptor site, they only show limited neurotrophic effects.

Method used

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  • Composition and use of Hubei crabapple and bamboo extract as active ingredients
  • Composition and use of Hubei crabapple and bamboo extract as active ingredients
  • Composition and use of Hubei crabapple and bamboo extract as active ingredients

Examples

Experimental program
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Effect test

preparation example Construction

[0114] Preparation of rutin standard solution: Weigh 15.0 mg of rutin reference substance dried at 105 °C under reduced pressure or normal pressure to constant weight, add methanol to dissolve and dilute to 100 mL, and make 150 μg / mL rutin standard solution.

[0115] 3. Measurement steps

[0116] 3.1 Drawing of standard curve

[0117] Accurately draw rutin standard solution 0, 0.50, 1.00, 2.00, 3.00, 4.00mL, equivalent to rutin 0, 75, 150, 300, 450, 600μg into a 10mL graduated colorimetric tube, add 30% ethanol solution to 5mL, Add 0.3mL of 5% sodium nitrite solution, shake and let stand for 5min, add 0.3mL of 10% aluminum nitrate solution, shake well and let stand for 6min, add 4mL of 1.0mol / L sodium hydroxide solution, dilute to 10mL with 30% ethanol , shake well and place it for 10 minutes; take the zero tube as a blank, measure the absorbance with a 1cm cuvette after shaking well at a wavelength of 510nm, draw a standard curve or obtain a linear regression with the absorb...

Embodiment 1

[0182] Embodiment 1, the tablet candy with Hubei crabapple and bamboo leaf flavonoids as main functional components

[0183] Take crabapple tea (dried leaves, water content ≤ 8%) to reach 80-100 mesh powder with a Chinese herbal medicine pulverizer, and then use nano-impact mill to make 800-1000 mesh micropowder to obtain crabapple leaf powder.

[0184] Take dried crabapple fruit (water content ≤ 10%) and use a Chinese herbal medicine pulverizer to obtain 80-100-mesh powder, and then use a nano-impact mill to make 800-1000-mesh micropowder to obtain crabapple powder.

[0185] The above-mentioned crabapple leaf powder and crabapple fruit powder were combined with other raw and auxiliary materials, and the mixture was evenly mixed, and then pressed into tablets. The formula composition is shown in Table 3. The net weight of each tablet is 0.8g, the total flavonoid content is ≥40mg / tablet, and the representative ingredients: 7,8-DHF, isoorientin, orientin, vitexin and isovitexin,...

Embodiment 2

[0206] Example 2, the solid beverage with Hubei crabapple fruit and its whole plant extract as the main functional component

[0207] The source and the preparation method of crabapple fruit powder are with embodiment 1.

[0208] Hubei Begonia CO 2 Preparation of supercritical extracts:

[0209] Grind the whole plant (including leaves, branches and roots) of Hubei Begonia after drying (moisture content ≤ 8%) into a coarse powder of about 20 meshes, take 5 kg and put it into the extraction kettle, heat up to 55 ° C, and start CO 2 Pump, pressurized to 30 MPa, enters the extraction kettle through the preheater; open the entrainer pump, make the acetone of 10% volume ratio (that is, the acetone of 100mL is used for every 1kg of the whole plant of Begonia hubei) through the preheating At the same time, it enters the extraction tank (ie, the extraction column shown in the figure below), and conducts dynamic extraction at 55°C for 3h. Separation kettle 1 sets separation pressure ...

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Abstract

The present invention discloses a composition using Malus hupehensis (Pamp.) Rehd and a bamboo extract as effective components, wherein the effective components of the composition comprise Malus hupehensis (Pamp.) Rehd and a bamboo extract, Malus hupehensis (Pamp.) Rehd is at least one selected from a Malus hupehensis (Pamp.) Rehd plant and a Malus hupehensis (Pamp.) Rehd extract, and the bamboo extract is at least one of the following seven components such as bamboo leaf flavone, bamboo leaf triterpene, bamboo shoot sterol, bamboo shoot oligopeptide, bamboo silicon, bamboo polysaccharide, and bamboo dietary fiber. The invention further provides uses of the composition, wherein the composition can be used for preparing functional food for prevention or treatment of any one disease selected from central obesity, premature / perimenopausal syndrome, Alzheimer disease and depression.

Description

technical field [0001] The present invention relates to the field of functional food in the food industry, and more specifically relates to the use of Hubei crabapple powder and its extracts and bamboo extracts (including bamboo leaf flavonoids, bamboo triterpenes, bamboo shoot sterols, bamboo shoot oligopeptides, bamboo silicon, bamboo polysaccharides, bamboo fiber, etc.), dietary supplements, functional foods, health foods, foods for special medical purposes, etc. Background technique [0002] Female menopause (40-55 years old) refers to a series of postmenopausal syndromes mainly characterized by autonomic nervous system dysfunction and accompanied by neuropsychological symptoms. Early menopause refers to a series of menopause-like symptoms that have occurred since the menopausal transition period due to excessive social pressure and other reasons before the age of 40. At present, the number of menopausal women in my country has reached 160 million, ranking first in the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P15/12A61P5/00A61P19/08A61P19/10A61P25/28A61P25/24A61P3/04A61K31/352A61K31/715
CPCA23C9/152A23G3/48A23L2/38A23L33/10A23L33/105A23L33/11A23L33/125A23L33/16A23L33/18A23L33/21A23V2002/00A61K31/352A61K31/715A61K36/73A61K36/899A61K2300/00A23V2200/3324A23V2200/306A23V2200/322A23V2200/31A23V2200/30A23V2250/21
Inventor 张英叶克强
Owner 杭州阡陌棠生物科技有限公司
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