Pharmaceutical composition for treating hashimoto thyroiditis and preparation method thereof

Abstract

The invention discloses a pharmaceutical composition (a formula capable of strengthening body resistance and removing stasis) for treating hashimoto thyroiditis and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of radix ginseng, 30 to 45 parts of radix astragali seu hedysari, 20 to 30 parts of radix et rhizoma salviae miltiorrhizae, 15 to 25 parts of liquorice root, 15 to 25 parts of white paeony root, 5 to 10 parts of dried tangerine peel and 5 to 10 parts of dried ginger. The pharmaceutical composition is prepared from raw materials which are both used as medicines and foods or can be used for health-care products, has no toxic side effect and has low cost. A drug effect test proves that the traditional Chinese medicine composition provided by the invention can be used for effectively repairing shapes of thyroid gland cells, reducing lymphocytes infiltration, remarkably reducing a thyroid autoantibody and a thyroid hormone level, reducing TNF-alpha (Tumor Necrosis Factor-alpha) and raising IL-10 and has a remarkable treatment effect on the hashimoto thyroiditis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating Hashimoto's thyroiditis and a preparation method thereof. Background technique [0002] Hashimoto's thyroiditis (HT) is the most common cause of hypothyroidism. It is an immune disease characterized by a large number of lymphocytes infiltrating the thyroid tissue and destruction of follicular cells. Serological tests show thyroid peroxidase antibodies (TPOAb), thyroglobulin antibody (TgAb) and free thyroxine (FT4) concentrations were significantly elevated. HT mostly occurs in women aged 30 to 50, with a male-to-female ratio of about 1:8. The current conventional therapy is hormone replacement therapy, but hormones have no immunoregulatory effect and cannot reduce the titer of thyroid autoantibodies, and patients need to take medication for life. Secondly, patients need constant physical examination,...

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine also has the disadvantages of high price and low output, which is not conducive to industrial application. At the same time, traditional Chinese medicine for the treatment of thyroid diseases mostly uses cold and cool drugs, which requires the patient's physical fitness, and its safety needs further confirmation, which is not conducive to Widely used, so there is a clinical need for new Chinese medicines for the treatment of Hashimoto's thyroiditis

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