Photothermal therapy probe based on photothermal nanomaterial

Abstract

The invention discloses a photothermal therapy probe based on a photothermal nanomaterial. The photothermal therapy probe comprises a cylindrical shell with a closed end, the photothermal nanomaterial arranged in the closed end in the shell, an optical fiber for illuminating the photothermal nanomaterial, and a temperature sensor close to the inner wall of the closed end of the shell. The shell is a hard material and provides the ability of the protection of internal devices and tissue puncture. An optical fiber guides laser into the internal part of a probe. The photothermal nanomaterial converts light energy into high-temperature heat energy, and the temperature sensor monitors and controls the terminal temperature of the probe. According to the photothermal therapy probe, the shell is filled with the photothermal nanomaterial, the light energy is converted into the heat energy, the probe reaches a tissue lesion part through minimal invasion, then through an efficient photothermal conversion mechanism of the photothermal nanomaterial, the killing of tumor and other disease tissue cells is implemented, and the photothermal therapy probe has the advantages of a simple structure, convenient operation, a small wound surface, efficient treatment and high accuracy.

Description

technical field [0001] The invention relates to the technical field of medical devices, a device for minimally invasive photothermal therapy, especially a photothermal therapy probe based on photothermal nanomaterials, which can be used to treat tumors and other lesions in different tissues and organs of the human body organize. Background technique [0002] Nanomaterial-mediated photothermal therapy is a new treatment method that converts light energy into heat energy through special nanomaterials to kill tumors and other diseased tissue cells through local high temperature. During the treatment, the nanomaterials need to be administered into the human body through intravenous infusion, and then the photothermal nanomaterials are enriched to the lesion site through the blood circulation, and then the lesion site is irradiated with laser light to implement time- and space-controllable photothermal therapy. At present, relevant photothermal nanomaterial preparations have ent...

AI Technical Summary

Problems solved by technology

At present, patents on photothermal therapy probes include ZL96101822.4; ZL02286746.5. The patents of these photothermal probes only introduce laser light into diseased tissue parts through transparent probes. These probes do not involve the application of photothermal nanomaterials. Their mechanism The treatment is carried out through the light energy absorbed by the lesion tissue and then converted into heat energy. The light-to-heat conversion efficiency of this mechanism is very low, and it cannot achieve a good therapeutic effect.

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