A kind of preparation method of alginate wound dressing with thrombin

Abstract

The invention relates to the field of medical care, in particular to a preparing method for sodium alginate wound application with thrombin. The preparing method comprises the following steps that an ethanol aqueous solution of the thrombin is configured, then sodium alginate long beam fiber is put into a reaction tank of the thrombin ethanol aqueous solution for constant temperature soaking, sodium alginate short fiber is prepared through drying and cutting after soaking, the short fiber is curled, non-woven fabrics are prepared through non-woven processes such as opening and scutching, carding, lapping and needling and cut into application cores of needed sizes, the application cores, silicone hydrogel membranes with holes, a polyurethane film adhesive tape and an anti-adhesive layer are composited through an application machine, and finally, a finished product of the sodium alginate wound application with the thrombin can be prepared. According to the composite application prepared through the preparing method, activity of the thrombin can be maintained to the utmost extent, the excellent hemostatic and absorption performance is achieved, meanwhile, adhesion of the application and wound can be prevented, a moist healing environment is provided for the surface of the wound, and wound healing is prompted.

Description

technical field [0001] The invention relates to the field of medical care, in particular to a preparation method of an alginate wound dressing with thrombin. Background technique [0002] The skin is the largest organ of the human body and the first line of defense between the human body and the external environment. It plays an important role in protecting the stability of the internal environment of the body and resisting the stimulation of the external environment and the invasion of pathogenic bacteria. [0003] In the field of medical care, researchers are paying more and more attention to how to better care for the skin, and the practicability and convenience of products are particularly important. Wound dressing has a good protective effect on the wound, avoiding secondary pollution from the outside, reducing the risk of infection for patients, and bringing many conveniences to people. [0004] However, the core of most application products is still relatively simple...

AI Technical Summary

Problems solved by technology

[0004] However, the core of most application products is still relatively simple. This kind of composite material only absorbs wound exudate when used on wounds, and cannot achieve the coexistence of wound moisturizing and hemostasis.

[0005] With the development of functional dressings, wound dressings are constantly improving. The single function of the product cannot meet the needs of clinical doctors and patients. For bleeding wounds, how to stop bleeding more effectively and effectively promote wound healing, To promote the growth of wound granulation, there is still no more effective product