Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Ultrasonic cell-breaking extraction technology for total polyphenol of Acanthopanax trifoliatus leaves

A technology of cell crushing and extraction process, which is applied in the direction of medical preparations containing active ingredients, anti-toxins, plant raw materials, etc.

Inactive Publication Date: 2017-12-01
ZHEJIANG SCI-TECH UNIV
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Bougainvillea contains many substances with antioxidant activity, anti-inflammatory, antibacterial, and anti-allergic properties, such as flavonoids. Studies have shown that Bougainvillea contains a certain amount of vitamin C (VC) and flavonoids, which are effective against nitrite. It has a certain scavenging effect and the ability to block the synthesis of nitrosamines, and related experiments have proved that the antioxidant activity of Bougainvillea is stronger than that of VC. A member of the edible plant anti-cancer health products; Wang Yan et al. quantitatively determined the antibacterial effect of total flavonoids of Bougainvillea, and the difference in the inhibitory effect on different fungi

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ultrasonic cell-breaking extraction technology for total polyphenol of Acanthopanax trifoliatus leaves
  • Ultrasonic cell-breaking extraction technology for total polyphenol of Acanthopanax trifoliatus leaves
  • Ultrasonic cell-breaking extraction technology for total polyphenol of Acanthopanax trifoliatus leaves

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0043] The following is an interpretation of the technical solution of the application in combination with specific cases, and the heating reflux method is used as a comparison to illustrate the effect of the technical solution.

[0044] 1. Experimental materials

[0045] 1.1 Experimental materials

[0046] The raw materials used in the experiment were white bougainvillea leaves, which were picked from Huichang County, Ganzhou, Jiangxi Province. The fresh and intact white bougainvillea leaves were selected and dried in an oven at no more than 60°C, and then sealed for storage.

[0047] 1.2 Experimental drugs

[0048] Chlorogenic acid standard (purity determined by HPLC-DAD> 99%, laboratory self-made), 4-CQA, 3,5-DCQA, 4,5-DCQA standard products (purity> 99%, purchased from Chengdu Pfeid Biotechnology Co., Ltd.); methanol (analytical purity), absolute ethanol (Hangzhou Gaojing Fine Chemical Co., Ltd.); Folin-Ciocalteu test solution (analytical purity) (Shanghai Ruji Biotech Development ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an ultrasonic cell-breaking extraction technology for total polyphenol of Acanthopanax trifoliatus leaves, and belongs to the technical field of the preparation containing drugs from plants. The technology comprises the following steps: pre-processing the Acanthopanax trifoliatus leaves, and placing in an ultrasonic synthesis extractor, adding ethyl alcohol, wherein the volume concentration of the ethyl alcohol is 20-90%, and ensuring that the liquid-to-solid ratio (ethyl alcohol volume: Acanthopanax trifoliatus leaf mass) is 40:1-120:1; starting the ultrasonic synthesis extractor, wherein the ultrasonic power is 400-1200 W, controlling the extraction temperature to be 30-60 DEG C, extracting for 10-50 min, taking out extracting solution and executing the extraction filtration, drying by distillation, and dissolving obtained powder under the ultrasonic condition, to obtain the extracted total polyphenol sample of the Acanthopanax trifoliatus leaves. The technology is applied for the polyphenol separation and purification of Acanthopanax trifoliatus stems and leaves and similar plants, and has the advantages of high purification efficiency and high polyphenol activity.

Description

Technical field [0001] The invention relates to an ultrasonic cell crushing extraction process for total polyphenols of white botanical leaves, belonging to the technical field of pharmaceutical preparations containing plants. Background technique [0002] White bobbin (Acanthopanan trifoliatus (L.) Merr.) is a climbing shrub of Araliaceae (Araliaceae) Araliaceae (Acanthopanax). Caffeoylquinic acid total polyphenols is one of the effective components of bobbin . White hairpin contains more anti-oxidant, anti-inflammatory, antibacterial, and anti-allergic substances, such as flavonoids. Studies have shown that white hairpin contains a certain amount of vitamin C (VC) and flavonoids. It has certain scavenging effect and the ability to block the synthesis of nitrosamines, and related experiments have proved that white bobbin has stronger antioxidant properties than VC. At the same time, the terpenoids in white bobbin have certain anti-cancer activity and may become A member of edi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/254A61P39/06A61K127/00
CPCA61K36/254A61K2236/15A61K2236/333A61K2236/51
Inventor 张晓丹祁哲晨吕洪飞修程蕾张维怡
Owner ZHEJIANG SCI-TECH UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com