Artificial muscle stent model as well as preparation device and method thereof

Abstract

The invention discloses an artificial muscle stent model as well as a preparation device and method thereof. The model comprises a lower stent, an upper stent and a cellular bundle layer, wherein the cellular bundle layer, the upper stent and the lower stent are distributed from top to bottom sequentially. The artificial muscle stent model prepared by the preparation device with the preparation method has the advantages of uniform cell arrangement, high cell survival rate and high printing precision.

Description

technical field [0001] The invention belongs to the fields of 3D printing technology and tissue engineering, and relates to an artificial muscle support model and a preparation device and method thereof. Background technique [0002] Tissue engineering is an interdisciplinary subject combining biomedicine and engineering that has emerged in recent years. Its core is to construct a complex composed of cells and biocompatible materials, and then apply it to damage tissues and organs. Repair to restore its functionality. 3D printing technology is processed and manufactured through material accumulation. Compared with traditional processing methods, 3D printing technology has greater advantages in the manufacture of complex structures, and at the same time has precise controllability. Engineering offers a whole new approach, which has been widely used in the field of biomedicine. [0003] The research purpose of the artificial muscle scaffold is mainly to use it for the repair...

AI Technical Summary

Problems solved by technology

[0005] For the above two manufacturing methods, artificial muscle tissue is obtained by planting muscle cells. With this method, the problem of uneven distribution of cells on silicon wafers or non-woven fabrics is likely to occur, so it is difficult to control the growth of skeletal muscle cells. Arrangement and three-dimensional tissue structure of artificial muscles, so it is difficult to meet the requirements of cell differentiation. At the same time, compared with direct printing, the implantation process is also more cumbersome

[0006] The application of 3D printing in tissue engineering provides a new method for the manufacture of artificial muscle tissue. Extrusion printing and inkjet printing are more widely used now. The former can obtain large pieces of artificial tissue through the accumulation of materials, but due to the During the printing process, the extrusion of the material will form a large shear force, which affects the cell survival rate, and the printing accuracy is low. Although the latter has the advantages of high cell survival rate and high printing accuracy, it is difficult to form a three-dimensional structure and cannot get chunks of artificial tissue

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