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Detecting method for traditional Chinese medicinal preparation for treating cold

A technology of traditional Chinese medicine preparations and detection methods, applied in measuring devices, instruments, scientific instruments, etc., can solve problems such as confusion, drug quality and adverse effects on curative effect, and achieve the effect of ensuring curative effect and safety, guaranteeing interests, and guaranteeing curative effect.

Active Publication Date: 2017-09-26
SICHUAN FENGCHUN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Another medicinal material used in a large amount is Artemisia annua, but Artemisia annua is easily confused with capillary and used as medicine, causing adverse effects on the quality and efficacy of medicines. Artemisia annua is the most common and most common. It is bitter, pungent, and cold in nature and taste, and returns to the liver, gallbladder, and kidney channels. , fever due to yin deficiency, bone steaming and labor pain, hot flashes in the afternoon, hot hands, feet, heart, exogenous summer heat, fever without sweating or sweating, dizziness and headache, thirsty and rapid pulse, or late febrile disease, warm evil enters Yin divides, hot at night and cool in the early morning, fever subsides without sweating or low fever persists after a febrile disease, etc., while Capillaris is the seedling of the perennial herb Artemisia capricariae or Artemisia chinensis in the family Asteraceae. Liver and gallbladder meridians, the main function is to clear away dampness and heat, reduce jaundice, and can also be used for eczema, itching, yellow water soaking, etc. The functions of the two are different, and corresponding detection methods must be used to distinguish them

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Prescription: Bupleurum 100g, Scutellaria baicalensis 149.4g, raw sun-dried ginseng 50g, licorice 100g, Pinellia 149.4g, dried ginger 100g, jujube 100g, Artemisia annua 149.4g.

[0030] Preparation method: the above eight flavors, extract the volatile oil from Bupleurum and dried ginger, the dregs of the medicine and the remaining scutellaria baicalensis and other six flavors, add water and decoct three times, the first time is 3 hours, the second time is 2 hours, the third time is 1 hour, and combined Decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.40, spray dry, add 446g of sucrose, 150g of dextrin, mix well, granulate with 70% ethanol, dry spray into volatile oil, mix well, that is, divide Each bag weighs 8g.

[0031] Properties: This product is brown granules; fragrant, sweet and slightly bitter.

[0032] Inspection: It should comply with the relevant regulations under the granule ("Chinese Pharmacopoeia" 2015 edition).

...

Embodiment 2

[0048] In this embodiment, except that step (1) to step (5) in the component identification method are different from embodiment 1, other methods are the same as embodiment 1.

[0049](1) The composition identification of wild cotton root is: take 8g of this product, add petroleum ether 50ml, soak for 30 minutes, ultrasonically treat for 40 minutes, filter, the filtrate evaporates to 2ml, and use it as the test solution; take another wild cotton root, Crush, add petroleum ether 50ml, soak for 30 minutes, sonicate for 40 minutes, filter, the filtrate evaporates to 2ml, and use it as a reference medicinal solution; according to the TLC test, draw 5μl of each of the above two solutions, and spot on the same silica gel G On a thin-layer board, use n-hexane:ethyl acetate=11:2 in volume ratio as the developer, develop, take out, dry in the air, spray with 10% phosphomolybdic acid ethanol solution, and heat at 105°C until the spots develop color Clear, in the chromatogram of the test...

Embodiment 3

[0055] In this embodiment, except that step (1) to step (5) in the component identification method are different from embodiment 1, other methods are the same as embodiment 1.

[0056] (1) The composition identification of wild cotton root is: take 8g of this product, add petroleum ether 30ml, soak for 10 minutes, ultrasonically treat for 20 minutes, filter, the filtrate evaporates to 2ml, and use it as the test solution; take another wild cotton root, Crush, add petroleum ether 30ml, soak for 10 minutes, sonicate for 20 minutes, filter, the filtrate evaporates to 2ml, and use it as the reference medicinal material solution; according to the thin-layer chromatography test, draw 5μl of each of the above two solutions, and spot on the same silica gel G On the thin-layer board, n-hexane: ethyl acetate = 8:0.8 in volume ratio is used as the developer, developed, taken out, dried in the air, sprayed with 10% phosphomolybdic acid ethanol solution, and heated at 105°C until the spots ...

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PUM

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Abstract

The invention relates to a detecting method for a traditional Chinese medicinal preparation for treating cold. The detecting method comprises the steps of identifying characters, checking, identifying components and determining the content, wherein the component identifying step comprises the following specific steps: identifying grape-leaved anemone roots, identifying radix scutellariae, identifying radix glycyrrhizae, identifying sun-dried radix ginseng, identifying herba artemisiae scopariae and identifying herba artemisiae apiaceae; the content identifying step means content determination of baicalin. Aiming at a current detecting method that more comprehensive monitoring of effective components of the traditional Chinese medicinal preparation cannot be realized, and interfusion of the grape-leaved anemone roots as a counterfeit drug and the herba artemisiae scopariae as a confused material cannot be monitored, the invention formulates a component identifying and content determining method with scientificity, reasonability and feasibility; by using the component identifying and content determining method, clinical curative effect of a medicine is ensured, several medicinal materials are enabled to have specific quality indexes, and use of all the medicinal materials in the medicine is ensured, thereby ensuring the curative effect of the medicine; besides, the grape-leaved anemone roots as the counterfeit drug of radix bupleuri and the herba artemisiae scopariae as the confused material of the herba artemisiae apiaceae can be effectively detected, and further the harm to the health of patients caused by toxic and harmful ingredients is avoided.

Description

technical field [0001] The invention relates to a detection method of a traditional Chinese medicine preparation, in particular to a detection method of a traditional Chinese medicine preparation for treating colds. Background technique [0002] Cold is a common exogenous disease in four seasons, especially in winter and spring. Many families have Chinese patent medicines for colds. Some people have taken a lot of medicines after suffering from colds, but the symptoms have not been alleviated. The key is that there is no syndrome differentiation. Medication, Chinese medicine believes that colds can generally be divided into two categories: wind-cold cold and wind-heat cold. The etiology, pathogenesis, symptoms, treatment principles and medication of these two kinds of colds are very different. [0003] Shaoyang Ganmao Granules is a variety recorded in the first volume of traditional Chinese medicine preparations in the "Drug Standards of the Ministry of Health". Traditional...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/90G01N30/94
CPCG01N30/90G01N30/94
Inventor 钟茂团古莉何德中林剑
Owner SICHUAN FENGCHUN PHARMA
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