Hyaluronic acid composition with anti-inflammatory and transdermal repairing effects and application

A technology of hyaluronic acid and composition, which is applied in the field of beauty, skin care and health care, can solve the problems of inability to deeply improve skin conditions, difficulty in treatment of skin diseases, poor treatment effect, etc., to speed up diffusion and absorption, prevent and solve skin problems Problems, the effect of strengthening skin immunity

Inactive Publication Date: 2017-09-19
海盾医美科技(杭州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the various skin beauty products only cover up the appearance and cannot deeply improve the condition of the skin. Most of the clinical treatment methods are oral hormones and sedative chemicals. The treatment effect is not good but the side effects are great. The treatment of diseases brings more difficulties. Therefore, for the treatment of skin beauty and skin diseases, especially chronic skin diseases, clinical treatment is still in the stage of symptomatic treatment, and a new generation of safe, effective and effective skin problem solutions is developed. is very necessary

Method used

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  • Hyaluronic acid composition with anti-inflammatory and transdermal repairing effects and application
  • Hyaluronic acid composition with anti-inflammatory and transdermal repairing effects and application
  • Hyaluronic acid composition with anti-inflammatory and transdermal repairing effects and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Embodiment one: hyaluronic acid composition solution

[0023] 1. Formula (weight ratio)

[0024] Hyaluronic Acid 1.0%

[0025] Compound 1 2.0%

[0026] Compound II 1.1%

[0027] Add deionized water to 100

[0028] 2. Production method (technical solution)

[0029] a. Dissolve hyaluronic acid and Compound II in 50g of deionized water at 37°C, stir and digest at 1000r / min for 3h, and adjust the pH to 5.5;

[0030] b. Add the compound to fully dissolve;

[0031] c. Add deionized water to 100 and mix evenly to obtain.

Embodiment 2

[0032] (2) Embodiment two: facial mask

[0033] 1. Formula (weight ratio)

[0034]

[0035]

[0036] 2. Production method (technical solution)

[0037] a. Take hyaluronic acid and compound two and dissolve them in 50g of deionized water at 37°C, stir and digest at 1000r / min for 3h, adjust the pH to 5.5, add compound one to fully dissolve;

[0038] b. After fully dissolving hydroxyethyl cellulose at 35°C, add it;

[0039]c. Add glycerin, butylene glycol, sorbitol, soluble olive oil, and polyethylene glycol 400 to the above solution in sequence, mix well, and fully dissolve;

[0040] d. Add EDTA-2Na phenoxyethanol, ethylhexylglycerin and essence to the above solution, mix well and fully dissolve;

[0041] e. Adjust the pH to 5.5 and set aside.

Embodiment 3

[0042] Embodiment three: bath effervescent tablet

[0043] 1. Formula (weight ratio)

[0044]

[0045] 2. Production method (technical solution)

[0046] a. Dry citric acid at 100°C for 2 hours, and sodium bicarbonate at 100°C for 2 hours, crush them through a 100-mesh sieve, mix well, seal and cool to 40°C;

[0047] b. Dissolve hyaluronic acid and compound 2 in 50g of deionized water at 37°C, stir and digest at 1000r / min for 3 hours, adjust pH to 5.5, add compound 1 to fully dissolve, spray dry into dry powder, add a and mix Uniform;

[0048] c. Add sodium chloride, sorbitol, peppermint, amino acid foaming agent, sodium benzoate, and essence to the above materials, mix evenly, grind, seal and dry in an oven at 60°C for 30 minutes;

[0049] d. Add polyethylene glycol 4000 sprayed with ethanol solution to the above materials, mix evenly, pass through a 140-mesh sieve, and put into a tablet machine for tablet compression to obtain effervescent tablets.

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PUM

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Abstract

The invention provides a hyaluronic acid composition with anti-inflammatory and transdermal repairing effects and application and belongs to the fields of beautifying, skin care and health care. The hyaluronic acid composition is prepared from the following components in percentage by weight: 0.5 percent to 3.0 percent of hyaluronic acid, 0.5 percent to 4.0 percent of a complex I, 0.1 percent to 2.0 percent of a complex II, 50 percent to 99 percent of de-ionized water and 1.0 percent to 50 percent of a substrate auxiliary material, wherein the compound I is prepared by compounding propylene glycol and borneol according to the mass ratio of 10 to 1 and is a transdermal accelerant; the complex II is prepared from recombinant human hyaluronidase (with the pH (Potential of Hydrogen) of 20), sodium chloride, calcium chloride and magnesium sulfate and the weight ratio of the components is 1 to 100 to 2 to 1 and has safe and efficient transdermal absorbency. A production method of the hyaluronic acid composition comprises the following steps: dissolving the hyaluronic acid and the complex II into 50g of the de-ionized water at 35 DEG C to 40 DEG C and stirring at the speed of 1000r / min to 3000r / min and digesting for 3h to 4h; adjusting the pH to be 5.0 to 5.6 and adding the complex I; adding the de-ionized water until the volume is 100 and uniformly mixing; preserving for later use; adding the substrate auxiliary material for shaping a product.

Description

technical field [0001] The invention belongs to the field of beauty, skin care and health care, and in particular relates to a hyaluronic acid composition with anti-inflammatory, antibacterial, transdermal and repairing effects and a preparation method thereof. Background technique [0002] With the continuous change of human life style, the constant change of living environment and the influence of factors such as age, psychological pressure, environmental pollution, seasonal changes, abuse of chemical products, etc., it has also brought many injuries to our skin and skin mucous membranes. The skin becomes rough and spots appear, and the incidence of skin diseases is on the rise. Modern medical research shows that the imbalance of human flora and the growth of pathogenic bacteria will lead to endocrine dysfunction, the increase of toxins in the body and the inability to discharge them in time, and inflammatory reactions in the body and on the skin surface, thus increasing t...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/66A61K8/34A61K8/23A61K8/20A61K8/04A61K8/02A61Q19/00A61Q17/00A61P17/00A61P37/04A61P29/00
CPCA61K8/735A61K8/0216A61K8/042A61K8/20A61K8/23A61K8/34A61K8/345A61K8/66A61K2800/5922A61Q17/005A61Q19/00
Inventor 贺晓军
Owner 海盾医美科技(杭州)有限公司
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