Quantitative calculation method for automatic regional brain shrinkage degree
A quantitative calculation and brain atrophy technology, applied in computing, image analysis, image data processing, etc., can solve the problem of lack of quantitative methods for the degree of brain atrophy, and achieve the effect of high degree of quantification, accurate judgment and high feasibility
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[0045] Collect the T1w structural magnetic resonance images of 100 normal elderly people aged 65±9 years old and 100 dementia patients aged 65±9 years old for experiments, and compare the brain regions of normal elderly people and dementia patients Atrophy of the brain. Specific steps are as follows:
[0046] Step S01. Perform non-linear registration and mapping between the T1w structural magnetic resonance images of normal elderly people and senile dementia patients and brain templates to obtain the space between each brain template and each individual (normal elderly people, senile dementia patients) transformation relationship;
[0047] Step S02. Map the brain lobe partition and brain tissue probability map on the brain template to the object space to be segmented;
[0048] Step S03. Use the STAPLE label fusion method to fuse the brain lobe partitions of each individual; select the brain tissue probability map of the template that is most similar to the target image after...
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