Method and system for pulmonary nodule detection, grading and management based on deep learning

A technology of deep learning and management system, applied in the field of pulmonary nodule detection grading and management and system based on deep learning, can solve the problem of few references, lack of guiding value in clinical treatment of nodules, and the diagnostic effect cannot reach the diagnostic efficiency of clinicians, etc. problem, to achieve the effect of scientific hierarchical management and diagnosis

Active Publication Date: 2020-12-29
SICHUAN CANCER HOSPITAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The deep neural convolutional network used for the diagnosis and classification of lung cancer disclosed in the above invention uses unsupervised training to diagnose pulmonary nodules, which has a certain role in auxiliary diagnosis in clinical use, but it does not affect the experience of clinicians (such as Follow-up of patients and follow-up management of pulmonary nodules) have few references, and adopt a simple classification diagnosis model without grading, its diagnostic effect cannot reach the diagnostic efficiency of clinicians, and it lacks guiding value for further clinical treatment of nodules

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  • Method and system for pulmonary nodule detection, grading and management based on deep learning
  • Method and system for pulmonary nodule detection, grading and management based on deep learning
  • Method and system for pulmonary nodule detection, grading and management based on deep learning

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Embodiment 1

[0050] Such as figure 1 , the present invention is a method for detecting, grading and managing pulmonary nodules based on deep learning, comprising the following steps:

[0051] S100: Collect ultra-low-dose spiral CT thin-slice images of the chest of several patients to form a CT image set, delineate the lung area in each CT image, and mark all the lung nodules in the lung area, and divide the lung nodules for grades 1-4;

[0052] S200: Based on the collected CT image set, as well as the lung area delineated in the CT image set, the marked pulmonary nodule and the grading information, sequentially train the lung area segmentation network, the suspected pulmonary nodule detection network, and the lung nodule screening and grading network; detect All CT images containing pulmonary nodules are obtained to obtain a CT image set of pulmonary nodules;

[0053] S300: Follow up the patients corresponding to the CT image set of pulmonary nodules, obtain the CT image sequences of the...

Embodiment 2

[0068] A pulmonary nodule detection, grading and management system based on deep learning, including a pulmonary nodule detection and grading module and a pulmonary nodule management module;

[0069] The pulmonary nodule detection and classification module includes a lung region segmentation network, a suspected pulmonary nodule detection network and a pulmonary nodule screening and classification network, which are used to accurately detect all pulmonary nodules from the image;

[0070] The lung region segmentation network is used to segment lung regions from chest low-dose spiral CT images;

[0071] The suspected pulmonary nodule detection network is used to detect suspected pulmonary nodules in the lung region;

[0072] The pulmonary nodule screening and grading network is used for screening and grading suspected pulmonary nodules;

[0073] The pulmonary nodule management module includes a pulmonary nodule management database and a lung cancer diagnosis network for diagnos...

Embodiment 3

[0077] Such as Figure 4 , for the detected pulmonary nodules, they are graded according to the clinical risk of the nodules, and the pulmonary nodules are divided into grades 1-4; if S / PS<5mm and NS<8mm, they are classified as grade 1; if S / PS 》5mm, and NS》8mm, it is classified as grade 2; if S / PS》15mm or NS》15mm, it is classified as grade 3; where S: solid nodule; PS: partially solid nodule; NS: non-solid nodule nodules;

[0078] The grade 2 nodules are reexamined after 3 months. If there is no change, they will be classified as grade 1. If the nodules increase, they will be consulted by multidisciplinary senior physicians to decide whether to enter clinical intervention. If no intervention is required, they will be classified as grade 1. Grade 1, if intervention is required, grade 4;

[0079] The grade 3 nodule will be re-examined one month after clinical treatment. If it is completely absorbed, it will be classified as grade 1. If it is not absorbed, it will be consulted...

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Abstract

The invention discloses a method for detecting, grading and managing pulmonary nodules based on deep learning, which is characterized in that it includes the following steps: S100: collecting ultra-low-dose spiral CT thin-layer images of the chest, delineating the lung area in the CT image, and marking out All lung nodules in the lung area; S200: train the lung area segmentation network, suspected lung nodule detection network and lung nodule screening and grading network; S300: obtain the time series of lung nodules and their corresponding grading for all patients in the image set Information labeling, constructing a pulmonary nodule management database; S400: Training a lung cancer diagnosis network based on a three-dimensional convolutional neural network and a long-term short-term memory network. Based on deep learning, the present invention trains the lung region segmentation network, suspected pulmonary nodule detection network, pulmonary nodule screening and grading network and lung cancer diagnosis network, accurately detects pulmonary nodules, and combines follow-up follow-up to obtain more accurate diagnosis Information and Clinical Strategies.

Description

technical field [0001] The present invention relates to the application of medical image diagnosis, database management, computer image processing, deep learning and other technologies in the screening and management of pulmonary nodules, especially a method and system for detecting, grading and managing pulmonary nodules based on deep learning. Background technique [0002] Lung cancer is one of the most important malignant tumors in my country. In the 2015 China Cancer Statistical Annual Report, there were 733,000 new cases of lung cancer (accounting for 17.1% of the total) and 610,000 deaths (accounting for 21.1% of the total). The rate and death rate take the first place, bringing huge losses to the health of the people and the country. At present, the 5-year survival rate of lung cancer is only 12% to 17%, and the 5-year survival rate of stage I lung cancer can reach more than 60%. Therefore, early detection of pulmonary nodules is the key to improving the survival rate ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16H50/20G06K9/46G06K9/62G06N3/04G06N3/08
CPCG16H50/20G06V10/464G06V2201/031G06F18/24G06F18/214
Inventor 周鹏张少霆任静青浩渺陈峥罗红兵胡仕北何长久
Owner SICHUAN CANCER HOSPITAL
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