Device and method for collecting and segmenting of hyperspectral images of unstainedpathological sections

Abstract

The invention discloses a device and method for collecting and segmenting of hyperspectral images of unstainedpathological sections. A section sample platform is supported in the middle of a bracket, the hyperspectral images of the unstainedpathological sectionsare automatically collected and processed through a computer, and lesion area segmentation resultsare obtained. Based on spectral difference caused by pathological changes of tissues, a personal computeris adopted to synchronously control relevant modules, spectral sequence images of the unstainedhistopathological sectionsare collected and preprocessed, and corresponding three-dimensionalhyperspectral dataare produced after overlaying;based the data and the combination with a currentlypopularneural network classificationthought, a spectral classification algorithm is developed to perform identity partitioning of a lesion area, thereby acceleratingthe identification rate and efficiency of the histopathological section, avoidingmanual errors which maybe brought during staining, and reducingthe time required by section making;automatic judgment is performed by utilizing a machine algorithm, therebyreducingsubjectivity caused by manual judgment. Therefore,a good auxiliary function is provided for a pathology doctor to detect the pathological sections.

Description

technical field [0001] The invention belongs to the field of detection devices, and in particular relates to a device and method for rapid collection and segmentation of non-stained pathological sections based on hyperspectral data. Background technique [0002] Pathological examination has been widely used in clinical work and scientific research. In the clinical aspect, the postmortem pathological examination and surgical pathological examination are mainly carried out. The purpose of surgical pathological examination is to clarify the diagnosis and verify the preoperative diagnosis and improve the level of clinical diagnosis; secondly, after the diagnosis is confirmed, the next treatment plan can be determined and the prognosis can be estimated, so as to improve the level of clinical treatment. Through clinical and pathological analysis, a large amount of extremely valuable scientific research data can also be obtained. [0003] A pathological slide is a type of patholo...

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Problems solved by technology

However, both of these two methods require staining of cancer sections, which still require high experimental and experience requirements for pathologists, and are time-consuming.

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