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Application of coenzyme Q10 combined ganoderma lucidum spore oil in preparation of antiatherosclerotic drugs

A technology of atherosclerosis and Ganoderma lucidum spore oil, which is applied in the field of medical treatment and medicine, can solve problems that have not been reported yet, achieve the effects of reducing adverse reactions, improving the effect of prevention and treatment, and overcoming the effect of insignificant curative effect

Inactive Publication Date: 2017-05-24
广东仁源健康管理有限公司 +1
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

So far, no ApoE has been seen in China - / - It is reported that mice were used to study anti-atherosclerosis of coenzyme Q10, and whether Ganoderma lucidum spore oil combined with coenzyme Q10 can improve the anti-atherosclerotic effect of coenzyme Q10 has not been reported at home and abroad.

Method used

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  • Application of coenzyme Q10 combined ganoderma lucidum spore oil in preparation of antiatherosclerotic drugs
  • Application of coenzyme Q10 combined ganoderma lucidum spore oil in preparation of antiatherosclerotic drugs
  • Application of coenzyme Q10 combined ganoderma lucidum spore oil in preparation of antiatherosclerotic drugs

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Embodiment Construction

[0019] In order to make the object, technical solution and effect of the present invention more clear and definite, the following examples are given to further describe the present invention in detail. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0020] The main experimental materials used in this embodiment are as follows:

[0021] Experimental animal: ApoE - / - Mice and wild-type (wide type, WT) mice with the same genetic background C57BL / 6, 6-8 weeks old, male, SPF grade, provided by Guangdong Provincial Laboratory Animal Monitoring Institute, tissue samples were obtained from Guangdong Provincial Laboratory Animal Monitoring [SYXK (Guangdong) 2012-0122] was carried out in the barrier animal experiment facility. The temperature of the breeding environment is 20±2°C, the humidity is 60±2%, and the lighting time is 12±3h. The feeding and disposal of animals during t...

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Abstract

The invention discloses a novel drug combination scheme for preventing and treating atherosclerosis, namely coenzyme Q10 and ganoderma lucidum spore oil combined medication. The administration scheme passes confirmation of animal models (suffering from hyperlipidemia and atherosclerosis), and the results show that the effect of the combined medication of the coenzyme Q10 and ganoderma lucidum spore oil for preventing and treating atherosclerosis or hyperlipidemia is obviously superior to that of single administration (coenzyme Q10). The combined medication can achieve the effects of obviously improving the effects of the coenzyme Q10 for preventing and treating the hyperlipidemia and atherosclerosis, reducing the dosage of the coenzyme Q10 and preventing adverse reactions, so that the defects that the curative effect is not obvious during single use of the coenzyme Q10 and side effects are caused due to high dosage of the coenzyme Q10 are overcome.

Description

technical field [0001] The invention relates to the field of medical treatment and medicine, in particular to the application of coenzyme Q10 combined with Ganoderma lucidum spore oil in the preparation of anti-atherosclerosis or prevention and treatment of hyperlipidemia drugs. Background technique [0002] With the improvement of people's living standards and changes in lifestyle, the death caused by infectious diseases has gradually decreased, while hyperlipidemia caused by high-fat diets and insufficient exercise has led to an increase in cardiovascular diseases such as arteriosclerosis, and tends to be younger. It has become the "number one killer" that threatens human health, and has caused serious losses to families and the social economy. Atherosclerosis (Atherosclerosis, AS) is the main pathological and physiological basis of cardiovascular diseases, and its essence is a chronic disease that accumulates a large amount of lipid and cholesterol in large and medium-siz...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61P9/10A61K31/122
CPCA61K31/122A61K36/074A61K2300/00
Inventor 黄韧杨丰华王静谭伟江唐林志李想陈小红
Owner 广东仁源健康管理有限公司
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