A high-speed countercurrent chromatograph with ring unwinding

Abstract

The invention discloses a high-speed countercurrent chromatograph with an unwound gear ring, which comprises an upper plate, a middle plate and a lower plate, and an unwound gear ring coaxial with the middle plate is fixed above the middle plate. The lower disc drives its rotation through a drive shaft, the unwinding gear ring is fixed, and the teeth of the unwinding gear ring are distributed on its inner ring, and there are multiple sets of meshing gears along the circumferential direction of the unwinding gear ring inner ring Gears, the gears between adjacent groups are not meshed, and each group of gears consists of two intermeshing gears, one of which drives a separation column, and the other gear drives an unwinding shaft, said separation column is mounted on a separation shaft On the top, the upper end of the unwinding shaft and the separation shaft are connected to the upper plate, and the lower end is connected to the middle plate; at the same time, the unwinding shaft and the separation column rotate with the rotating bracket; after the liquid inlet pipe passes through the central axis of the upper plate and the middle plate, it is sequentially After connecting multiple groups of separation columns and infusion tubes of uncoiled shafts in series, it is finally discharged from the liquid outlet tube.

Description

technical field [0001] The invention relates to the field of separation and analysis instruments, in particular to a high-speed countercurrent chromatograph with an unwound gear ring. Background technique [0002] High-speed countercurrent chromatography is a liquid-liquid partition chromatography without solid support packing, and the separation is realized according to the difference in the distribution coefficient of the components to be separated in the upper and lower phases. The principle is to use the centrifugal force generated by the spiral tube during planetary motion to continuously mix the immiscible two-phase solvents, distribute the samples multiple times, and achieve separation according to the different partition coefficients of the substances to be separated. Because there is no need for any solid carrier or support, it can achieve high-efficiency separation and preparation in a short time, and can reach thousands of theoretical plates. Compared with other ...

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Problems solved by technology

[0004] The countercurrent chromatograph with this structure: 1. It is easy to cause excessive force on the central gear, and the long-term operation causes the central shaft where the central gear is located to shake, resulting in poor stability of the instrument; 2. At the same time, due to the existence of the revolving gear and the central shaft, the instrument The β value of β cannot be further increased, which leads to the limitation of the function of the instrument; 3. In the high-speed countercurrent chromatograph, the R size is an important parameter, and the R size of the conventional high-speed countercurrent chromatograph is usually fixed and cannot be adjusted. The design of the gear ring structure can adjust the size of the gears in the separation column and the unwinding shaft, so that it is convenient to adjust the R size and broaden the use range of the instrument

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